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Molecular filter-nanosieve

Neal, Terrell D. and Scherer, Axel (2002) Molecular filter-nanosieve. In: Micro Total Analysis Systems 2002. Vol.2. Springer , Dordrecht, pp. 781-783. ISBN 978-94-010-3953-6. https://resolver.caltech.edu/CaltechAUTHORS:20191204-135517310

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Abstract

Demonstrated in this paper is a molecular sieve. The focus of this work is making a “smart” filter. This filter has electrochemical and electromechanical properties that would allow both sorting and filtering of solutions. Prior sifters and sieving structures have been at the mercy of a static material structure, whereas the convention proposed here allows dynamic control of filtering size during an assay. The filter mechanism simply relies on a sandwiched layer of oxide, grown in a RF Sputtering system. This allows for almost Angstrom level control of the thickness. An oxide layer is sandwiched between two layers of silicon with e-beam written holes 100nm in diameter, one offset from the other. Dry etching is used to carve these holes in the silicon layers, and wet oxide etching defines a void in the sandwiched layer. The distance that the two silicon layers are separated dictates the smallest filtering size. Analysis is available through several methods. Mechanically, a fluid can be passed through the holes carrying along with it the particles or molecules that are small enough to make it through the oxide layer. Electrochemically, a charged particle can be placed on one side of a container and separated by the filter, while having the tendency to get to the other side, with different concentration, by passing through the filter [1].


Item Type:Book Section
Related URLs:
URLURL TypeDescription
https://doi.org/10.1007/978-94-010-0504-3_60DOIArticle
https://rdcu.be/b3ZFePublisherFree ReadCube access
Additional Information:© 2002 Springer Science+Business Media Dordrecht. Terrell D. Neal was supported by the David Lucille Packard Foundation Fellowship. This work was supported by the National Science Foundation under grant BES-0119493, and by the Army Research Office under contract DAAD19-00-1-0392. We also wish to thank Jim Hone and Ali Husain for their thoughtful suggestions.
Funders:
Funding AgencyGrant Number
David and Lucile Packard FoundationUNSPECIFIED
NSFBES-0119493
Army Research Office (ARO)DAAD19-00-1-0392
Subject Keywords:microfluidic; filter; sieve; molecular; nanopore; nanofluidic
DOI:10.1007/978-94-010-0504-3_60
Record Number:CaltechAUTHORS:20191204-135517310
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20191204-135517310
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:100186
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:04 Dec 2019 22:04
Last Modified:16 Nov 2021 17:52

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