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Amygdala-enriched genes identified by microarray technology are restricted to specific amygdaloid subnuclei

Supplementary material for Zirlinger et al. (2001) Proc. Natl. Acad. Sci. USA98 (9), 5270-5275. (10.1073/pnas.091094698)

 

Table 4. Categories of genes among differentially expressed genes in the brain

 

 

Amy

Cb

Hpc

OB

PAG

Total

Enriched genes

33

159

89

101

73

455

No. of annotated genes

8

47

17

24

21

117

% of annotated genes/enriched

24

30

19

24

29

26

 

Molecular function

Total no. of genes

% genes

% in Amy

% in Cb

% in Hpc

% in OB

% in PAG

Motor protein

1

1

13

0

0

0

0

Ribonuclear

2

2

0

4

0

0

0

Nuclear

1

1

0

2

0

0

0

Signaling

30

26

25

30

0

29

33

Transporter

3

3

0

4

0

0

5

Ligand binding or carrier

8

7

0

9

6

8

5

DNA binding

20

17

50

17

12

17

10

Structural

10

9

0

6

18

17

0

Enzyme

18

15

0

15

18

8

29

Enzyme inhibitor

4

3

0

4

0

4

5

Membrane protein

6

5

13

4

0

4

10

Ubiquitin

2

2

0

0

6

4

0

Immunity, defense protein

1

1

0

0

6

0

0

Zinc finger protein

2

2

0

0

12

0

0

Cell adhesion

1

1

0

0

6

0

0

Chaperone

1

1

0

0

6

0

0

Translation

5

4

0

2

6

8

5

Cell cycle regulator

1

1

0

2

0

0

0

Transcription factor binding

1

1

0

0

6

0

0

Here, 117 genes were annotated and classified based on molecular function among the 455 total genes identified to be differentially enriched in our screen (117/455 = 26%). Guidelines from the Gene Ontology (GO) Consortium were followed.