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A Cortical Region Consisting Entirely of Face-Selective Cells

Tsao, Doris Y. and Freiwald, Winrich A. and Tootell, Roger B. H. and Livingstone, Margaret S. (2006) A Cortical Region Consisting Entirely of Face-Selective Cells. Science, 311 (5761). pp. 670-674. ISSN 0036-8075. PMCID PMC2678572. https://resolver.caltech.edu/CaltechAUTHORS:20200121-083323880

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Abstract

Face perception is a skill crucial to primates. In both humans and macaque monkeys, functional magnetic resonance imaging (fMRI) reveals a system of cortical regions that show increased blood flow when the subject views images of faces, compared with images of objects. However, the stimulus selectivity of single neurons within these fMRI-identified regions has not been studied. We used fMRI to identify and target the largest face-selective region in two macaques for single-unit recording. Almost all (97%) of the visually responsive neurons in this region were strongly face selective, indicating that a dedicated cortical area exists to support face processing in the macaque.


Item Type:Article
Related URLs:
URLURL TypeDescription
https://doi.org/10.1126/science.1119983DOIArticle
https://www.sciencemag.org/cgi/content/full/311/5761/670/DC1PublisherSupporting Information
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678572PubMed CentralArticle
ORCID:
AuthorORCID
Tsao, Doris Y.0000-0003-1083-1919
Additional Information:© 2006 American Association for the Advancement of Science. Received 9 September 2005; accepted 5 December 2005. We thank B. Moghaddam and T. Poggio for discussions; D. Hubel, C. Gross, and G. Yovel for comments on the manuscript; T. Chuprina, D. Freeman, S. Moeller, N. Nallasamy, N. Schweers, W. Vanduffel, and members of the Massachusetts General Hospital monkey fMRI group for technical assistance; and A. Dale and A. van der Kouwe for allowing us to use their multiecho sequence and undistortion algorithm. This work was supported by NIH (grant nos. EY13135 and EY13025), P41:RR14075, and the Mental Illness and Neuroscience Discovery (MIND) Institute. D.Y.T is supported by a Sofia Kovalevksaya Award from the Alexander von Humboldt Foundation.
Funders:
Funding AgencyGrant Number
NIHEY13135
NIHEY13025
NIHP41:RR14075
Mental Illness and Neuroscience Discovery (MIND) InstituteUNSPECIFIED
Alexander von Humboldt FoundationUNSPECIFIED
Issue or Number:5761
PubMed Central ID:PMC2678572
Record Number:CaltechAUTHORS:20200121-083323880
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20200121-083323880
Official Citation:A Cortical Region Consisting Entirely of Face-Selective Cells. BY DORIS Y. TSAO, WINRICH A. FREIWALD, ROGER B. H. TOOTELL, MARGARET S. LIVINGSTONE. SCIENCE 03 FEB 2006 : 670-674; doi: 10.1126/science.1119983
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:100808
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:21 Jan 2020 17:46
Last Modified:27 Apr 2021 19:37

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