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Investigating the Post-Partum Flare in Rheumatoid Arthritis Using Transcriptome Analysis

Wright, Matthew and Goin, Dana and Smed, Mette and Pachter, Lior and Nelson, J. Lee and Jewell, Nicholas and Olsen, Jørn and Hetland, Merete Lund and Zoffmann, Vibeke and Jawaheer, Damini (2019) Investigating the Post-Partum Flare in Rheumatoid Arthritis Using Transcriptome Analysis. Arthritis and Rheumatology, 71 (S10). Art. No. 1940. ISSN 2326-5191. doi:10.1002/art.41108.

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Women with Rheumatoid arthritis (RA) tend to have a predictable fl are of disease activity in the months after childbirth. The mechanism(s) underlying this post-partum fl are are as yet unknown. Using our pregnancy cohort, we (a) examined gene expression changes associated with a fl are of RA disease activity post- partum, (b) determined how those changes compare to post- partum changes observed among healthy women, and (c) examined whether expression profi les by 3 months post- partum differed from those before pregnancy.

Item Type:Article
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Pachter, Lior0000-0002-9164-6231
Additional Information:© 2019 American College of Rheumatology. Issue Online: 29 October 2019; Version of Record online: 29 October 2019. Disclosure: M. Wright , None; D. Goin , None; M. Smed , None; L. Pachter , None; J. Nelson , None; N. Jewell , None; J. Olsen , None; M. Lund Hetland , Abbvie, 2, AbbVie, 2, Biogen, 2, BMS, 2, CellTrion, 2, 9, MSD, 2, Novartis, 2, Orion, 2, Pfi zer, 2, Samsung, 2, UCB, 2; V. Zoffmann , None; D. Jawaheer , None.
Issue or Number:S10
Record Number:CaltechAUTHORS:20200206-130336877
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Official Citation:(2019), Abstract Supplement 2019 ACR/ARP Annual Meeting. Arthritis Rheumatol, 71: 1-5420. doi:10.1002/art.41108
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:101174
Deposited By: Tony Diaz
Deposited On:06 Feb 2020 21:11
Last Modified:16 Nov 2021 18:00

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