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Total synthesis of natural product antibiotics

Reisman, Sarah E. (2020) Total synthesis of natural product antibiotics. In: 259th ACS National Meeting & Exposition, 22-26 March 2020, Philadelphia, PA.

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Since the discovery of the antibiotic penicillin, natural products-small mols. isolated from plants, bacteria, and fungi-have played an essential role in the development of new anti-infectives. Synthetic org. chemists can use Nature's mols. as a starting point, and perform precise mol. edits to make new mols. with improved the properties or efficacy. Although semisynthesis has given rise to the vast majority of natural product-derived antibiotics, total synthesis can provide opportunities to prep. new derivs. not accessible through semi-synthesis. This seminar will describe recent efforts in our lab. focused on the synthesis of natural product antibiotics.

Item Type:Conference or Workshop Item (Paper)
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Reisman, Sarah E.0000-0001-8244-9300
Additional Information:© 2020 American Chemical Society.
Record Number:CaltechAUTHORS:20200219-113059736
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:101378
Deposited By: Tony Diaz
Deposited On:19 Feb 2020 19:41
Last Modified:19 Feb 2020 19:41

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