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Mapping chain unfolding in macromolecular networks under stress

Baccile, Joshua and Tirrell, David Anthony (2020) Mapping chain unfolding in macromolecular networks under stress. In: 259th ACS National Meeting & Exposition, 22-26 March 2020, Philadelphia, PA.

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We have prepd. well-defined macromol. networks that contain engineered fibronectin domains that unfold when subjected to mech. stress. Unfolding of the network chains can be monitored by observing changes in Forster resonance energy transfer (FRET) between pairs of dyes that flank the fibronectin domains. This lecture will describe the spatial mapping of FRET efficiency in protein hydrogels subject to non-uniform mech. stress fields.

Item Type:Conference or Workshop Item (Paper)
Related URLs:
URLURL TypeDescription Website
Baccile, Joshua0000-0003-4334-755X
Tirrell, David Anthony0000-0003-3175-4596
Additional Information:© 2020 American Chemical Society.
Record Number:CaltechAUTHORS:20200219-113331019
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:101379
Deposited By: Tony Diaz
Deposited On:19 Feb 2020 19:40
Last Modified:19 Feb 2020 19:40

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