Li, Lei and Wu, Zhiguang and Yang, Yiran and Hu, Peng and Gao, Wei and Wang, Lihong V. (2020) Photoacoustic computed tomography guided microrobots for targeted navigation in intestines in vivo. In: Photons Plus Ultrasound: Imaging and Sensing 2020. Proceedings of SPIE. No.11240. Society of Photo-Optical Instrumentation Engineers (SPIE) , Art. No. 112402R. ISBN 9781510632431. https://resolver.caltech.edu/CaltechAUTHORS:20200220-134102759
![[img]](https://authors.library.caltech.edu/style/images/fileicons/application_pdf.png) |
PDF
- Published Version
See Usage Policy. 536kB |
Use this Persistent URL to link to this item: https://resolver.caltech.edu/CaltechAUTHORS:20200220-134102759
Abstract
Tremendous progress in synthetic micro/nanomotors has been made for potential biomedical applications. However, existing micro/nanomotor platforms are inefficient for deep tissue imaging and motion control in vivo. Here, we present a photoacoustic computed tomography (PACT) guided investigation of micromotors in intestines in vivo. The micromotors enveloped in microcapsules exhibit efficient propulsion in various biofluids once released. PACT has visualized the migration of micromotor capsules toward the targeted regions in real time in vivo. The integration of the developed microrobotic system and PACT enables deep imaging and precise control of the micromotors in vivo.
| Item Type: | Book Section | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Related URLs: |
| ||||||||||||
| ORCID: |
| ||||||||||||
| Additional Information: | © 2020 Society of Photo-Optical Instrumentation Engineers (SPIE). This work was sponsored by the Startup funds from California Institute of Technology (to W.G.) and the NIH grants EB016986 (NIH Director’s Pioneer Award), CA186567 (NIH Director’s Transformative Research Award), NS090579, and NS099717 (all to L.V.W.). We gratefully acknowledge critical support and infrastructure provided for this work by the Kavli Nanoscience Institute at Caltech. | ||||||||||||
| Group: | Kavli Nanoscience Institute | ||||||||||||
| Funders: |
| ||||||||||||
| Subject Keywords: | Photoacoustic computed tomography; microrobots; in vivo navigation | ||||||||||||
| Series Name: | Proceedings of SPIE | ||||||||||||
| Issue or Number: | 11240 | ||||||||||||
| DOI: | 10.1117/12.2547559 | ||||||||||||
| Record Number: | CaltechAUTHORS:20200220-134102759 | ||||||||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20200220-134102759 | ||||||||||||
| Official Citation: | Lei Li, Zhiguang Wu, Yiran Yang, Peng Hu, Wei Gao, and Lihong V. Wang "Photoacoustic computed tomography guided microrobots for targeted navigation in intestines in vivo", Proc. SPIE 11240, Photons Plus Ultrasound: Imaging and Sensing 2020, 112402R (17 February 2020); https://doi.org/10.1117/12.2547559 | ||||||||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||||||||
| ID Code: | 101427 | ||||||||||||
| Collection: | CaltechAUTHORS | ||||||||||||
| Deposited By: | Tony Diaz | ||||||||||||
| Deposited On: | 20 Feb 2020 21:48 | ||||||||||||
| Last Modified: | 16 Nov 2021 18:02 |
Repository Staff Only: item control page
