Wei, Lu and Miao, Kun and Du, Jiajun (2020) Stimulated Raman imaging with chemical probes for subcellular bioanalysis (Conference Presentation). In: Advanced Chemical Microscopy for Life Science and Translational Medicine. Proceedings of SPIE. No.11252. Society of Photo-optical Instrumentation Engineers (SPIE) , Bellingham, WA, Art. No. 112521S. ISBN 9781510632677. https://resolver.caltech.edu/CaltechAUTHORS:20200311-151707274
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Abstract
Innovations in optical spectroscopy and microscopy have revolutionized our understanding in biological systems at sub-cellular levels. In this talk, I will discuss about our recent development by coupling stimulated Raman scattering (SRS) microscopy with chemical probes that could allow new subcellular bioanalysis in live cells. The introduced tags offer additional SRS contrast channel for quantification of biological contents that were previously difficult. Both physical and chemical principles underlying the optical microscopy will be presented, as well as our efforts in biomedical applications including cancer- and neuronal- metabolism.
| Item Type: | Book Section | ||||||
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| Additional Information: | © 2020 Society of Photo-Optical Instrumentation Engineers (SPIE). | ||||||
| Series Name: | Proceedings of SPIE | ||||||
| Issue or Number: | 11252 | ||||||
| DOI: | 10.1117/12.2546942 | ||||||
| Record Number: | CaltechAUTHORS:20200311-151707274 | ||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20200311-151707274 | ||||||
| Official Citation: | Lu Wei, Kun Miao, and Jiajun Du "Stimulated Raman imaging with chemical probes for subcellular bioanalysis (Conference Presentation)", Proc. SPIE 11252, Advanced Chemical Microscopy for Life Science and Translational Medicine, 112521S (10 March 2020); https://doi.org/10.1117/12.2546942 | ||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||
| ID Code: | 101861 | ||||||
| Collection: | CaltechAUTHORS | ||||||
| Deposited By: | George Porter | ||||||
| Deposited On: | 11 Mar 2020 22:48 | ||||||
| Last Modified: | 16 Nov 2021 18:06 |
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