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Posterior Parietal Cortex Encodes Autonomously Selected Motor Plans

Cui, He and Andersen, Richard A. (2007) Posterior Parietal Cortex Encodes Autonomously Selected Motor Plans. Neuron, 56 (3). pp. 552-559. ISSN 0896-6273. PMCID PMC2651089. doi:10.1016/j.neuron.2007.09.031. https://resolver.caltech.edu/CaltechAUTHORS:20200331-140611914

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Abstract

The posterior parietal cortex (PPC) of rhesus monkeys has been found to encode the behavioral meaning of categories of sensory stimuli. When animals are instructed with sensory cues to make either eye or hand movements to a target, PPC cells also show specificity depending on which effector (eye or hand) is instructed for the movement. To determine whether this selectivity retrospectively reflects the behavioral meaning of the cue or prospectively encodes the movement plan, we trained monkeys to autonomously choose to acquire a target in the absence of direct instructions specifying which effector to use. Activity in PPC showed strong specificity for effector choice, with cells in the lateral intraparietal area selective for saccades and cells in the parietal reach region selective for reaches. Such differential activity associated with effector choice under identical stimulus conditions provides definitive evidence that the PPC is prospectively involved in action selection and movement preparation.


Item Type:Article
Related URLs:
URLURL TypeDescription
https://doi.org/10.1016/j.neuron.2007.09.031DOIArticle
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651089PubMed CentralArticle
ORCID:
AuthorORCID
Andersen, Richard A.0000-0002-7947-0472
Additional Information:© 2007 Elsevier Inc. Received 13 July 2007, Revised 13 September 2007, Accepted 26 September 2007, Available online 7 November 2007. We thank R. Battacharyya, C. Buneo, J. Cho, E. Hwang, and S. Musallam for help during data collection; D. Baldauf, G. Mulliken, and H. Scherberger for helpful discussions during the course of this study; M. Campos, I. Kagan, and D. Rizzuto for valuable comments on the manuscript; K. Pejsa, N. Sammons, and L. Martel for help with animal handling and training; J. Baer and C. Lindsell for veterinary assistance; V. Shcherbatyuk for computer support; and T. Yao for administrative support. This work was supported by National Eye Institute (NEI) and the James G. Boswell Foundation.
Funders:
Funding AgencyGrant Number
National Eye InstituteUNSPECIFIED
James G. Boswell FoundationUNSPECIFIED
NIHUNSPECIFIED
Subject Keywords:SYSNEURO
Issue or Number:3
PubMed Central ID:PMC2651089
DOI:10.1016/j.neuron.2007.09.031
Record Number:CaltechAUTHORS:20200331-140611914
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20200331-140611914
Official Citation:He Cui, Richard A. Andersen, Posterior Parietal Cortex Encodes Autonomously Selected Motor Plans, Neuron, Volume 56, Issue 3, 2007, Pages 552-559, ISSN 0896-6273, https://doi.org/10.1016/j.neuron.2007.09.031. (http://www.sciencedirect.com/science/article/pii/S0896627307007659)
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:102208
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:31 Mar 2020 21:27
Last Modified:16 Nov 2021 18:09

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