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Time-invariant reference frames for parietal reach activity

Buneo, Christopher A. and Batista, Aaron P. and Jarvis, Murray R. and Andersen, Richard A. (2008) Time-invariant reference frames for parietal reach activity. Experimental Brain Research, 188 (1). pp. 77-89. ISSN 0014-4819. doi:10.1007/s00221-008-1340-x.

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Neurophysiological studies suggest that the transformation of visual signals into arm movement commands does not involve a sequential recruitment of the various reach-related regions of the cerebral cortex but a largely simultaneous activation of these areas, which form a distributed and recurrent visuomotor network. However, little is known about how the reference frames used to encode reach-related variables in a given “node” of this network vary with the time taken to generate a behavioral response. Here we show that in an instructed delay reaching task, the reference frames used to encode target location in the parietal reach region (PRR) and area 5 of the posterior parietal cortex (PPC) do not evolve dynamically in time; rather the same spatial representation exists within each area from the time target-related information is first instantiated in the network until the moment of movement execution. As previously reported, target location was encoded predominantly in eye coordinates in PRR and in both eye and hand coordinates in area 5. Thus, the different computational stages of the visuomotor transformation for reaching appear to coexist simultaneously in the parietal cortex, which may facilitate the rapid adjustment of trajectories that are a hallmark of skilled reaching behavior.

Item Type:Article
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Andersen, Richard A.0000-0002-7947-0472
Additional Information:© 2008 Springer-Verlag. Received 18 July 2007; Accepted 29 February 2008; Published 27 March 2008. The authors wish to thank Betty Gillikin, Kelsie Pejsa, Lea Martel and Viktor Shcherbatyuk for technical assistance, Janet Baer and Janna Wynne for veterinary care and Cierina Marks and Tessa Yao for administrative assistance. This work was supported by the J. G. Boswell Foundation, the Sloan-Swartz Center for Theoretical Neurobiology, the National Eye Institute (NEI), the Defense Advanced Research Projects Agency (DARPA), and the Office of Naval Research (ONR).
Funding AgencyGrant Number
James G. Boswell FoundationUNSPECIFIED
Sloan-Swartz Center for Theoretical NeurobiologyUNSPECIFIED
National Eye InstituteUNSPECIFIED
Defense Advanced Research Projects Agency (DARPA)UNSPECIFIED
Office of Naval Research (ONR)UNSPECIFIED
Subject Keywords:Monkey; Cortex; Arm; Coordinates; Transformations
Issue or Number:1
Record Number:CaltechAUTHORS:20200401-070246216
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Official Citation:Buneo, C.A., Batista, A.P., Jarvis, M.R. et al. Time-invariant reference frames for parietal reach activity. Exp Brain Res 188, 77–89 (2008).
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:102211
Deposited By: Tony Diaz
Deposited On:01 Apr 2020 15:32
Last Modified:16 Nov 2021 18:09

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