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Center–Surround Antagonism Based on Disparity in Primate Area MT

Bradley, David C. and Andersen, Richard A. (1998) Center–Surround Antagonism Based on Disparity in Primate Area MT. Journal of Neuroscience, 18 (18). pp. 7552-7565. ISSN 0270-6474. PMCID PMC6793235. https://resolver.caltech.edu/CaltechAUTHORS:20200401-152855581

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Abstract

Most neurons in primate visual area MT have a large, modulatory region surrounding their classically defined receptive field, or center. The velocity tuning of this “surround” is generally antagonistic to the center, making it potentially useful for detecting image discontinuities on the basis of differential motion. Because classical MT receptive fields are also disparity-selective, one might expect to find disparity-based surround antagonism as well; this would provide additional information about image discontinuities. However, the effects of disparity in the MT surround have not been studied previously. We measured single-neuron responses to variable-disparity moving patterns in the MT surround while holding a central moving pattern at a fixed disparity. Of the 130 neurons tested, 84% exhibited a modulatory surround, and in 52% of these, responses were significantly affected by disparity in the surround. In most cases, disparity effects in the surround were antagonistic to the center; that is, neurons were generally suppressed when center and surround stimuli had the same disparity, with decreasing suppression as the center and surround stimuli became separated in depth. Also, the effects of disparity and direction were mainly additive; i.e., disparity effects were generally independent of direction, and vice versa. These results suggest that the MT center–surround apparatus provides information about image discontinuities, not only on the basis of velocity differences but on the basis of depth differences as well. This supports the hypothesis that MT surrounds have a role in image segmentation.


Item Type:Article
Related URLs:
URLURL TypeDescription
https://doi.org/10.1523/jneurosci.18-18-07552.1998DOIArticle
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6793235PubMed CentralArticle
ORCID:
AuthorORCID
Andersen, Richard A.0000-0002-7947-0472
Additional Information:© 1998 Society for Neuroscience. Beginning six months after publication the Work will be made freely available to the public on SfN’s website to copy, distribute, or display under a Creative Commons Attribution 4.0 International (CC BY 4.0) license (https://creativecommons.org/licenses/by/4.0/). Received Nov. 19, 1997; revised June 30, 1998; accepted July 1, 1998. This work was supported by grants from the National Eye Institute, the Human Frontier Science Program, and the Sloan Foundation for Theoretical Neurobiology. We are grateful to G. Robertson, D. Ward, B. Gillikin, and S. Gertemanian for technical assistance, and to K. Shenoy for comments on this manuscript.
Funders:
Funding AgencyGrant Number
National Eye InstituteUNSPECIFIED
Human Frontier Science ProgramUNSPECIFIED
Sloan-Swartz Center for Theoretical NeurobiologyUNSPECIFIED
NIHUNSPECIFIED
Subject Keywords:middle temporal area; motion perception; receptive field surrounds; image segmentation; primate; velocity tuning
Issue or Number:18
PubMed Central ID:PMC6793235
Record Number:CaltechAUTHORS:20200401-152855581
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20200401-152855581
Official Citation:Center–Surround Antagonism Based on Disparity in Primate Area MT. David C. Bradley, Richard A. Andersen. Journal of Neuroscience 15 September 1998, 18 (18) 7552-7565; DOI: 10.1523/JNEUROSCI.18-18-07552.1998
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:102254
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:01 Apr 2020 22:33
Last Modified:01 Apr 2020 22:33

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