El-Nachef, Wael and Bronner, Marianne (2020) De novo neurogenesis in the post-embryonic zebrafish enteric nervous system from Schwann cell precursors rather than resident cell types. Neurogastroenterology and Motility, 32 (S1). Art. No. 29. ISSN 1350-1925. doi:10.1111/nmo.13817. https://resolver.caltech.edu/CaltechAUTHORS:20200409-140201559
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Abstract
The enteric nervous system (ENS) is essential for normal gastrointestinal motility, and defects in its function define several difficult to treat conditions. While the developmental origin of the ENS from neural crest cells is well understood, there is conflicting evidence regarding postnatal enteric neurogenesis and neuronal homeostasis. Using zebrafish as a model due to its simplified ENS which is amenable to live-imaging, we sought to explore the origin of enteric neurons that arise in post-embryonic life in both normal development and upon injury, and tested effects of the 5-HT₄ receptor agonist, prucalopride, in this process.
Item Type: | Article | |||||||||
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Additional Information: | © 2020 The Authors. Neurogastroenterology & Motility © 2020 John Wiley & Sons Ltd. Issue Online: 22 March 2020; Version of Record online: 22 March 2020. | |||||||||
Issue or Number: | S1 | |||||||||
DOI: | 10.1111/nmo.13817 | |||||||||
Record Number: | CaltechAUTHORS:20200409-140201559 | |||||||||
Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20200409-140201559 | |||||||||
Official Citation: | (2020), Poster Presentations. Neurogastroenterology & Motility, 32: e13817. doi:10.1111/nmo.13817 | |||||||||
Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | |||||||||
ID Code: | 102461 | |||||||||
Collection: | CaltechAUTHORS | |||||||||
Deposited By: | Tony Diaz | |||||||||
Deposited On: | 09 Apr 2020 21:13 | |||||||||
Last Modified: | 16 Nov 2021 18:12 |
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