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Neural correlates of cognitive motor signals in primary somatosensory cortex

Jaffari, Matiar and Aflalo, Tyson and Chivukula, Srinivas and Kellis, Spencer S. and Armenta Salas, Michelle and Norman, Sumner L. and Pejsa, Kelsie and Liu, Charles Y. and Andersen, Richard A. (2020) Neural correlates of cognitive motor signals in primary somatosensory cortex. . (Unpublished) https://resolver.caltech.edu/CaltechAUTHORS:20200422-071051130

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Abstract

Classical systems neuroscience positions primary sensory areas as early feed-forward processing stations for refining incoming sensory information. This view may oversimplify their role given extensive bi-directional connectivity with multimodal cortical and subcortical regions. Here we show that single units in human primary somatosensory cortex encode imagined reaches centered on imagined limb positions in a cognitive motor task. This result suggests a broader role of primary somatosensory cortex in cortical function than previously demonstrated.


Item Type:Report or Paper (Discussion Paper)
Related URLs:
URLURL TypeDescription
https://doi.org/10.1101/2020.04.20.041269DOIDiscussion Paper
ORCID:
AuthorORCID
Kellis, Spencer S.0000-0002-5158-1058
Armenta Salas, Michelle0000-0002-0634-2891
Andersen, Richard A.0000-0002-7947-0472
Additional Information:The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission. Posted April 21, 2020. This work was supported by the National Institute of Health (R01EY015545, 5U01NS098975-02), the Tianqiao and Chrissy Chen Brain-machine Interface Center at Caltech, the Conte Center for Social Decision Making at Caltech (P50MH094258), the David Geffen Medical Scholarship, and the Boswell Foundation. The authors would also like to thank subject FG for participating in the studies, and Viktor Scherbatyuk for technical assistance. Author Contributions: M.J., T.A, and R.A.A designed the study, M.J. and T.A developed experimental tasks, M.J. and T.A. designed analysis and analyzed the data, M.J., S.C., S.S.K, and M.A.S. collected the data, S.L.N contributed code, M.J. and T.A. interpreted results and wrote the original draft, M.J., T.A., S.C., and R.A.A. reviewed and edited the paper, T.A. and R.A.A. provided mentorship, T.A., S.K., and R.A.A. acquired funding, K.P provided administrative and regulatory assistance, C.Y.L. performed implantation surgery. Data availability: All primary behavioral and neurophysiological data are archived in the Division of Biology and Biological Engineering at the California Institute of Technology and are available from the corresponding author on reasonable request. Code availability: All custom-written analysis code is available from the corresponding author on reasonable request.
Group:Tianqiao and Chrissy Chen Institute for Neuroscience
Funders:
Funding AgencyGrant Number
NIHR01EY015545
NIH5U01NS098975-02
Tianqiao and Chrissy Chen Institute for NeuroscienceUNSPECIFIED
Caltech Conte Center for the Neurobiology of Social Decision MakingUNSPECIFIED
NIHP50MH094258
David Geffen Medical ScholarshipUNSPECIFIED
James G. Boswell FoundationUNSPECIFIED
Record Number:CaltechAUTHORS:20200422-071051130
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20200422-071051130
Official Citation:Neural correlates of cognitive motor signals in primary somatosensory cortex. Matiar Jaffari, Tyson Aflalo, Srinivas Chivukula, Spencer Kellis, Michelle Armenta Salas, Sumner Norman, Kelsie Pejsa, Charles Liu, Richard A Andersen. bioRxiv 2020.04.20.041269; doi: https://doi.org/10.1101/2020.04.20.041269
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:102707
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:22 Apr 2020 15:30
Last Modified:22 Apr 2020 15:30

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