Stancovski, Ilana and Baltimore, David (1997) NF-κB Activation: The IκB Kinase Revealed? Cell, 91 (3). pp. 299-302. ISSN 0092-8674. doi:10.1016/s0092-8674(00)80413-4. https://resolver.caltech.edu/CaltechAUTHORS:20200423-120625235
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Abstract
More than a decade ago, the transcriptional activator NF-κB was described as a protein that bound to a specific DNA site in the intronic enhancer of the immunoglobulin κ light chain gene (Sen and Baltimore 1986). Following the cloning of genes encoding the p50 and p65 subunits of NF-κB, it became evident that both subunits are members of the larger NF-κB/Rel family of transcriptional regulator proteins. Since its initial description, our view of the role of NF-κB in immune and inflammatory responses has broadened significantly (for reviews, see 1, 2).
Item Type: | Article | ||||||
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Additional Information: | © 1997 Cell Press. Under an Elsevier user license. | ||||||
Issue or Number: | 3 | ||||||
DOI: | 10.1016/s0092-8674(00)80413-4 | ||||||
Record Number: | CaltechAUTHORS:20200423-120625235 | ||||||
Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20200423-120625235 | ||||||
Official Citation: | Ilana Stancovski, David Baltimore, NF-κB Activation: The IκB Kinase Revealed?, Cell, Volume 91, Issue 3, 1997, Pages 299-302, ISSN 0092-8674, https://doi.org/10.1016/S0092-8674(00)80413-4. | ||||||
Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||
ID Code: | 102749 | ||||||
Collection: | CaltechAUTHORS | ||||||
Deposited By: | George Porter | ||||||
Deposited On: | 23 Apr 2020 19:32 | ||||||
Last Modified: | 16 Nov 2021 18:15 |
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