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Unnatural amino acid mutagenesis in mapping ion channel function

Beene, Darren L. and Dougherty, Dennis A. and Lester, Henry A. (2003) Unnatural amino acid mutagenesis in mapping ion channel function. Current Opinion in Neurobiology, 13 (3). pp. 264-270. ISSN 0959-4388. https://resolver.caltech.edu/CaltechAUTHORS:20200427-123619296

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Abstract

Unnatural amino acid mutagenesis makes possible the site-specific incorporation of synthetic amino acids, enabling detailed structure–function studies as well as the incorporation of biophysical probes. This method has been adapted for use with heterologous expression in Xenopus oocytes, allowing experiments on ion channels.


Item Type:Article
Related URLs:
URLURL TypeDescription
https://doi.org/10.1016/s0959-4388(03)00068-0DOIArticle
ORCID:
AuthorORCID
Dougherty, Dennis A.0000-0003-1464-2461
Lester, Henry A.0000-0002-5470-5255
Additional Information:© 2003 Elsevier Science Ltd. Available online 11 June 2003.
Issue or Number:3
Record Number:CaltechAUTHORS:20200427-123619296
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20200427-123619296
Official Citation:Darren L Beene, Dennis A Dougherty, Henry A Lester, Unnatural amino acid mutagenesis in mapping ion channel function, Current Opinion in Neurobiology, Volume 13, Issue 3, 2003, Pages 264-270, ISSN 0959-4388, https://doi.org/10.1016/S0959-4388(03)00068-0. (http://www.sciencedirect.com/science/article/pii/S0959438803000680)
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:102806
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:27 Apr 2020 19:59
Last Modified:27 Apr 2020 19:59

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