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Coupling Cell Growth, Proliferation, and Death: Hippo Weighs In

Hay, Bruce A. and Guo, Ming (2003) Coupling Cell Growth, Proliferation, and Death: Hippo Weighs In. Developmental Cell, 5 (3). pp. 361-363. ISSN 1534-5807. doi:10.1016/s1534-5807(03)00270-3.

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Four recent papers describe the characterization in Drosophila of Hippo, a serine/threonine kinase of the Sterile 20 (STE20) group, resembling Mst1 and Mst2. Hippo restricts cell growth and cell proliferation, promotes cell death, and interacts with the tumor suppressors Salvador and Warts. This, together with the ability of Mst2 to rescue hippo mutant phenotypes, argues that Mst/Hippo proteins are tumor suppressors.

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Additional Information:© 2003 Cell Press. Available online 11 September 2003.
Issue or Number:3
Record Number:CaltechAUTHORS:20200428-144140100
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Official Citation:Bruce A Hay, Ming Guo, Coupling Cell Growth, Proliferation, and Death: Hippo Weighs In, Developmental Cell, Volume 5, Issue 3, 2003, Pages 361-363, ISSN 1534-5807, (
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:102888
Deposited By: Tony Diaz
Deposited On:28 Apr 2020 21:53
Last Modified:16 Nov 2021 18:16

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