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Cell proliferation and apoptosis

Guo, Ming and Hay, Bruce A. (1999) Cell proliferation and apoptosis. Current Opinion in Cell Biology, 11 (6). pp. 745-752. ISSN 0955-0674. doi:10.1016/s0955-0674(99)00046-0.

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Cell proliferation and cell death are essential yet opposing cellular processes. Crosstalk between these processes promotes a balance between proliferation and death, and it limits the growth and survival of cells with oncogenic mutations. New insights into the mechanisms by which strong signals to proliferate and activation of cyclin-dependent kinases promote apoptosis have recently been published, and a novel cell cycle regulated caspase inhibitor, Survivin, has been described.

Item Type:Article
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Additional Information:© 1999 Elsevier Science Ltd. Available online 28 January 2000.
Subject Keywords:Proliferation; Apoptosis; Oncogene; E2F-1; Cyclin dependent kinases (cdk)
Issue or Number:6
Record Number:CaltechAUTHORS:20200428-153223416
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Official Citation:Ming Guo, Bruce A Hay, Cell proliferation and apoptosis, Current Opinion in Cell Biology, Volume 11, Issue 6, 1999, Pages 745-752, ISSN 0955-0674, (
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:102893
Deposited By: Tony Diaz
Deposited On:28 Apr 2020 22:53
Last Modified:16 Nov 2021 18:16

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