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Effect of viewing distance on object responses in macaque areas 45B, F5a and F5p

Caprara, I. and Janssen, P. (2020) Effect of viewing distance on object responses in macaque areas 45B, F5a and F5p. . (Unpublished) https://resolver.caltech.edu/CaltechAUTHORS:20200505-153340976

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Abstract

To perform real-world tasks like grasping, the primate brain has to process visual object information so that the grip aperture can be adjusted before contact with the object is made. Previous studies have demonstrated that the posterior subsector of the Anterior Intraparietal area (pAIP) is connected to frontal area 45B, and the anterior subsector of AIP (aAIP) to F5a (Premereur et al., 2015). However, the role of area 45B and F5a in visually-guided object grasping is poorly understood. Here, we investigated the role of area 45B, F5a and F5p in visually-guided grasping. If a neuronal response to an object during passive fixation represents the activation of a motor command related to the preshaping of the hand, such neurons should prefer objects presented within reachable distance. Conversely, neurons encoding a pure visual representation of an object should be less affected by viewing distance. Contrary to our expectations, we found that the majority of neurons in area 45B were object- and viewing distance selective, with a clear preference for the near viewing distance. Area F5a showed much weaker object selectivity compared to 45B, with a similar preference for objects presented at the Near position emerging mainly in the late epoch. Finally, F5p neurons were less object selective and frequently preferred objects presented at the Far position. Therefore, contrary to our expectations, neurons in area 45B - but not F5p neurons - prefer objects presented in peripersonal space.


Item Type:Report or Paper (Discussion Paper)
Related URLs:
URLURL TypeDescription
https://doi.org/10.1101/2020.05.04.070862DOIDiscussion Paper
ORCID:
AuthorORCID
Caprara, I.0000-0002-2031-861X
Janssen, P.0000-0002-8463-5577
Additional Information:The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission. Posted May 05, 2020. This work was supported by Fonds voor Wetenschappelijk Onderzoek Vlaanderen (Odysseus grant G.0007.12 and grant G0A8516N). We thank Stijn Verstraeten, Piet Kayenbergh, Gerrit Meulemans, Marc De Paep, Astrid Hermans, Christophe Ulens and Inez Puttemans for assistance, and Steve Raiguel for comments on a previous version of this manuscript. The authors declare no competing financial interests.
Funders:
Funding AgencyGrant Number
Fonds voor Wetenschappelijk Onderzoek (FWO)G.0007.12
Fonds voor Wetenschappelijk Onderzoek (FWO)G0A8516N
Record Number:CaltechAUTHORS:20200505-153340976
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20200505-153340976
Official Citation:Effect of viewing distance on object responses in macaque areas 45B, F5a and F5p. Irene Caprara, Peter Janssen. bioRxiv 2020.05.04.070862; doi: https://doi.org/10.1101/2020.05.04.070862
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:103009
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:05 May 2020 22:39
Last Modified:05 May 2020 22:39

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