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Cellular latency of human immunodeficiency virus type 1

Pomerantz, Roger J. and Bagasra, Omar and Baltimore, David (1992) Cellular latency of human immunodeficiency virus type 1. Current Opinion in Immunology, 4 (4). pp. 475-480. ISSN 0952-7915. doi:10.1016/s0952-7915(06)80042-7. https://resolver.caltech.edu/CaltechAUTHORS:20200513-155012262

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Abstract

The infection of humans by human immunodeficiency virus type 1 is characterized by a prolonged stage of clinical quiescence. This clinically asymptomatic period may be based, in part, on the development of cell populations within the body that maintain human immunodeficiency virus type 1 in a state of latency. Recent advances in the understanding of the molecular mechanisms involved in various forms of cellular latency of human immunodeficiency virus type 1 have begun to shed light on the variable period of asymptomatic infection. The elucidation of cellular retroviral latency, in vivo, will also be critical to the design of novel therapeutic approaches with which to combat human immunodeficiency virus type 1 infections.


Item Type:Article
Related URLs:
URLURL TypeDescription
https://doi.org/10.1016/s0952-7915(06)80042-7DOIArticle
ORCID:
AuthorORCID
Baltimore, David0000-0001-8723-8190
Additional Information:© 1992 Published by Elsevier Ltd. The authors wish to thank Didier Trono, for helpful discussions and Rita Victor for excellent secretarial assistance. This work was supported in part by U.S. Public Health Service Grant AI 00930 (RJP).
Funders:
Funding AgencyGrant Number
NIHAI00930
Issue or Number:4
DOI:10.1016/s0952-7915(06)80042-7
Record Number:CaltechAUTHORS:20200513-155012262
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20200513-155012262
Official Citation:Roger J. Pomerantz, Omar Bagasra, David Baltimore, Cellular latency of human immunodeficiency virus type 1, Current Opinion in Immunology, Volume 4, Issue 4, 1992, Pages 475-480, ISSN 0952-7915, https://doi.org/10.1016/S0952-7915(06)80042-7. (http://www.sciencedirect.com/science/article/pii/S0952791506800427)
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:103192
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:13 May 2020 23:04
Last Modified:16 Nov 2021 18:19

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