Pomerantz, Roger J. and Bagasra, Omar and Baltimore, David (1992) Cellular latency of human immunodeficiency virus type 1. Current Opinion in Immunology, 4 (4). pp. 475-480. ISSN 0952-7915. doi:10.1016/s0952-7915(06)80042-7. https://resolver.caltech.edu/CaltechAUTHORS:20200513-155012262
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Abstract
The infection of humans by human immunodeficiency virus type 1 is characterized by a prolonged stage of clinical quiescence. This clinically asymptomatic period may be based, in part, on the development of cell populations within the body that maintain human immunodeficiency virus type 1 in a state of latency. Recent advances in the understanding of the molecular mechanisms involved in various forms of cellular latency of human immunodeficiency virus type 1 have begun to shed light on the variable period of asymptomatic infection. The elucidation of cellular retroviral latency, in vivo, will also be critical to the design of novel therapeutic approaches with which to combat human immunodeficiency virus type 1 infections.
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Additional Information: | © 1992 Published by Elsevier Ltd. The authors wish to thank Didier Trono, for helpful discussions and Rita Victor for excellent secretarial assistance. This work was supported in part by U.S. Public Health Service Grant AI 00930 (RJP). | ||||||
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Issue or Number: | 4 | ||||||
DOI: | 10.1016/s0952-7915(06)80042-7 | ||||||
Record Number: | CaltechAUTHORS:20200513-155012262 | ||||||
Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20200513-155012262 | ||||||
Official Citation: | Roger J. Pomerantz, Omar Bagasra, David Baltimore, Cellular latency of human immunodeficiency virus type 1, Current Opinion in Immunology, Volume 4, Issue 4, 1992, Pages 475-480, ISSN 0952-7915, https://doi.org/10.1016/S0952-7915(06)80042-7. (http://www.sciencedirect.com/science/article/pii/S0952791506800427) | ||||||
Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||
ID Code: | 103192 | ||||||
Collection: | CaltechAUTHORS | ||||||
Deposited By: | Tony Diaz | ||||||
Deposited On: | 13 May 2020 23:04 | ||||||
Last Modified: | 16 Nov 2021 18:19 |
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