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Viral RNA-dependent DNA Polymerase: RNA-dependent DNA Polymerase in Virions of RNA Tumour Viruses

Baltimore, David (1970) Viral RNA-dependent DNA Polymerase: RNA-dependent DNA Polymerase in Virions of RNA Tumour Viruses. Nature, 226 (5252). pp. 1209-1211. ISSN 0028-0836. https://resolver.caltech.edu/CaltechAUTHORS:20200514-160705278

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Abstract

Two independent groups of investigators have found evidence of an enzyme in virions of RNA tumour viruses which synthesizes DNA from an RNA template. This discovery, if upheld, will have important implications not only for carcinogenesis by RNA viruses but also for the general understanding of genetic transcription: apparently the classical process of information transfer from DNA to RNA can be inverted.


Item Type:Article
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https://doi.org/10.1038/2261209a0DOIArticle
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ORCID:
AuthorORCID
Baltimore, David0000-0001-8723-8190
Additional Information:© 1970 Nature Publishing Group. Received 02 June 1970; Issue Date 27 June 1970. I thank Drs G. Todaro, F. Rauscher and R. Holdenreid for their assistance in providing the mouse leukaemia virus. This work was supported by grants from the US Public Health Service and the American Cancer Society and was carried out during the tenure of an American Society Faculty Research Award.
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American Cancer SocietyUNSPECIFIED
Issue or Number:5252
Record Number:CaltechAUTHORS:20200514-160705278
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20200514-160705278
Official Citation:Baltimore, D. Viral RNA-dependent DNA Polymerase: RNA-dependent DNA Polymerase in Virions of RNA Tumour Viruses. Nature 226, 1209–1211 (1970). https://doi.org/10.1038/2261209a0
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:103218
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:14 May 2020 23:45
Last Modified:14 May 2020 23:45

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