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Skin-Interfaced Sensors in Digital Medicine: from Materials to Applications

Xu, Changhao and Yang, Yiran and Gao, Wei (2020) Skin-Interfaced Sensors in Digital Medicine: from Materials to Applications. Matter, 2 (6). pp. 1414-1445. ISSN 2590-2385. PMCID PMC7274218.

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The recent advances in skin-interfaced wearable sensors have enabled tremendous potential toward personalized medicine and digital health. Compared with traditional healthcare, wearable sensors could perform continuous and non-invasive data collection from the human body and provide an insight into both fitness monitoring and medical diagnostics. In this review, we summarize the latest progress of skin-interfaced wearable sensors along with their integrated systems. We first introduce the strategies of materials selection and structure design that can be accommodated for intimate contact with human skin. Current development of physical and biochemical sensors is then classified and discussed with an emphasis on their sensing mechanisms. System-level integration including power supply, wireless communication, and data analysis are also briefly discussed. We conclude with an outlook of this field and identify the key challenges and opportunities for future wearable devices and systems.

Item Type:Article
Related URLs:
URLURL TypeDescription CentralArticle
Yang, Yiran0000-0001-8770-8746
Gao, Wei0000-0002-8503-4562
Additional Information:© 2020 Elsevier Inc. Available online 3 June 2020. This work was supported by the Rothenberg Innovation Initiative (RI2) program at California Institute of Technology (Caltech), Caltech – City of Hope Biomedical Research Initiative, the Amgen Chem-Bio-Engineering Award, and National Institutes of Health grant 5R21NR018271. Author Contributions: Conceptualization, W.G.; Investigation, C.X.; Writing – Original Draft, C.X. and Y.Y.; Writing – Review & Editing, C.X., Y.Y., and W.G.; Supervision, W.G.
Funding AgencyGrant Number
Rothenberg Innovation Initiative (RI2)UNSPECIFIED
Caltech-City of Hope Biomedical InitiativeUNSPECIFIED
Subject Keywords:soft materials; flexible electronics; wearable sensors; electronic skin; digital health
Issue or Number:6
PubMed Central ID:PMC7274218
Record Number:CaltechAUTHORS:20200603-134306977
Persistent URL:
Official Citation:Changhao Xu, Yiran Yang, Wei Gao, Skin-Interfaced Sensors in Digital Medicine: from Materials to Applications, Matter, Volume 2, Issue 6, 2020, Pages 1414-1445, ISSN 2590-2385, (
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:103674
Deposited By: Tony Diaz
Deposited On:03 Jun 2020 20:52
Last Modified:06 Aug 2020 18:38

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