A Caltech Library Service

Spatiotemporal Antialiasing in Photoacoustic Computed Tomography

Hu, Peng and Li, Lei and Lin, Li and Wang, Lihong V. (2020) Spatiotemporal Antialiasing in Photoacoustic Computed Tomography. IEEE Transactions on Medical Imaging, 39 (11). pp. 3535-3547. ISSN 0278-0062. PMCID PMC7654731.

[img] PDF - Published Version
See Usage Policy.


Use this Persistent URL to link to this item:


Photoacoustic computed tomography (PACT) based on a full-ring ultrasonic transducer array is widely used for small animal wholebody and human organ imaging, thanks to its high in-plane resolution and full-view fidelity. However, spatial aliasing in full-ring geometry PACT has not been studied in detail. If the spatial Nyquist criterion is not met, aliasing in spatial sampling causes artifacts in reconstructed images, even when the temporal Nyquist criterion has been satisfied. In this work, we clarified the source of spatial aliasing through spatiotemporal analysis. We demonstrated that the combination of spatial interpolation and temporal filtering can effectively mitigate artifacts caused by aliasing in either image reconstruction or spatial sampling, and we validated this method by both numerical simulations and in vivo experiments.

Item Type:Article
Related URLs:
URLURL TypeDescription
Hu, Peng0000-0002-2933-1239
Li, Lei0000-0001-6164-2646
Lin, Li0000-0002-0517-8436
Wang, Lihong V.0000-0001-9783-4383
Additional Information:© 2020 IEEE. Manuscript received April 11, 2020; accepted May 24, 2020. Date of publication May 29, 2020; date of current version October 28, 2020. This work was sponsored by National Institutes of Health Grants R01 CA186567 (NIH Director’s Transformative Research Award), R01 NS102213, U01 NS099717 (BRAIN Initiative), and R35 CA220436 (Outstanding Investigator Award). The authors appreciate the close reading of the manuscript by Professor James Ballard. Lihong V. Wang has financial interests in Microphotoacoustics, Inc., CalPACT, LLC, and Union Photoacoustic Technologies, Ltd., which did not support this work.
Funding AgencyGrant Number
NIHR01 CA186567
NIHR01 NS102213
NIHU01 NS099717
NIHR35 CA220436
Subject Keywords:Photoacoustic computed tomography, spatiotemporal antialiasing, spatial interpolation, temporal filtering
Issue or Number:11
PubMed Central ID:PMC7654731
Record Number:CaltechAUTHORS:20200605-131724922
Persistent URL:
Official Citation:P. Hu, L. Li, L. Lin and L. V. Wang, "Spatiotemporal Antialiasing in Photoacoustic Computed Tomography," in IEEE Transactions on Medical Imaging, vol. 39, no. 11, pp. 3535-3547, Nov. 2020, doi: 10.1109/TMI.2020.2998509
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:103733
Deposited By: Tony Diaz
Deposited On:05 Jun 2020 21:07
Last Modified:02 Dec 2020 18:13

Repository Staff Only: item control page