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DNA-functionalized scaffolds for drug capture applications

Schulz, Michael D. and Blumenfeld, Carl M. and Grubbs, Robert H. and Greer, Julia R. and Yee, Daryl Wei Liang (2020) DNA-functionalized scaffolds for drug capture applications. Patent number: US10646505B2. https://resolver.caltech.edu/CaltechAUTHORS:20200608-101206169

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Abstract

This disclosure is directed to structured compositions, including DNA-functionalized scaffolds, for drug capture, and methods and devices for sequestering chemotherapeutics from physiological fluids using the functionalized scaffolds.


Item Type:Patent
Related Patents:US20180064747A1
Patent Classification:Current U.S. Class: 1/1. Current CPC Class: C08F 222/10 (20130101); A61L 29/085 (20130101); A61L 31/14 (20130101); A61K 47/58 (20170801); A61K 47/6929 (20170801); C08F 293/005 (20130101); A61K 47/6923 (20170801); A61K 31/711 (20130101); A61K 47/549 (20170801); A61L 29/16 (20130101); A61L 31/10 (20130101); A61L 31/08 (20130101); A61L 31/16 (20130101); A61L 2300/258 (20130101); A61L 2400/12 (20130101). Current International Class: A61K 31/711 (20060101); C08F 293/00 (20060101); A61L 31/14 (20060101); A61L 31/10 (20060101); A61L 31/08 (20060101); A61K 47/58 (20170101); A61K 47/69 (20170101); A61K 47/54 (20170101); A61L 29/16 (20060101); A61L 31/16 (20060101); C08F 222/10 (20060101); A61L 29/08 (20060101) .
Patent Assignee:California Institute of Technology
Related URLs:
URLURL TypeDescription
http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=10646505.PN.&OS=PN/10646505&RS=PN/10646505PatentU.S. Patent Office
ORCID:
AuthorORCID
Schulz, Michael D.0000-0001-8499-6025
Grubbs, Robert H.0000-0002-0057-7817
Greer, Julia R.0000-0002-9675-1508
Yee, Daryl Wei Liang0000-0002-4114-6167
Additional Information:Application filed: September 6, 2017. Patent granted: May 12, 2020. GOVERNMENT RIGHTS: This invention was made with government support under Grant No. CA194533 awarded by the National Institute of Health and under Grant No. DE-SC0006599 awarded by the Department of Energy. The government has certain rights in the invention. CROSS-REFERENCE TO RELATED APPLICATIONS: This application claims the benefit of priority from U.S. Patent Application Ser. No. 62/384,625, filed Sep. 7, 2016, and U.S. Patent Application Ser. No. 62/399,621, filed Sep. 26, 2016, the contents of which are both incorporated by reference herein for all purposes.
Funders:
Funding AgencyGrant Number
NIHCA194533
Department of Energy (DOE)DE-SC0006599
Record Number:CaltechAUTHORS:20200608-101206169
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20200608-101206169
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:103742
Collection:CaltechAUTHORS
Deposited By: Katherine Johnson
Deposited On:08 Jun 2020 17:25
Last Modified:19 Nov 2020 00:42

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