Lundin, Pamela M. and Esquivias, Jorge and Fu, Gregory C. (2008) Catalytic Asymmetric Cross-Couplings of Racemic α-Bromoketones with Arylzinc Reagents. Angewandte Chemie International Edition, 48 (1). pp. 154-156. ISSN 1433-7851. PMCID PMC2790061. doi:10.1002/anie.200804888. https://resolver.caltech.edu/CaltechAUTHORS:20200626-123754710
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Abstract
Nickel box : The first catalytic asymmetric method for cross‐coupling arylzinc reagents with α‐bromoketones has been developed (see scheme). This stereoconvergent carbon–carbon bond‐forming process occurs under unusually mild conditions and without activators, thereby allowing the generation of potentially labile tertiary stereocenters.
Item Type: | Article | ||||||||||
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Additional Information: | © 2009 WILEY‐VCH. Received: October 6, 2008. Published online: November 28, 2008. Support has been provided by the National Institutes of Health (National Institute of General Medical Sciences, grant R01‐GM62871), Merck Research Laboratories, Novartis, and the Spanish Department of Science (fellowship for J.E.). | ||||||||||
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Subject Keywords: | asymmetric catalysis · enantioselectivity · ketones · nickel · zinc | ||||||||||
Issue or Number: | 1 | ||||||||||
PubMed Central ID: | PMC2790061 | ||||||||||
DOI: | 10.1002/anie.200804888 | ||||||||||
Record Number: | CaltechAUTHORS:20200626-123754710 | ||||||||||
Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20200626-123754710 | ||||||||||
Official Citation: | Lundin, P., Esquivias, J. and Fu, G. (2009), Catalytic Asymmetric Cross‐Couplings of Racemic α‐Bromoketones with Arylzinc Reagents. Angew. Chem. Int. Ed., 48: 154-156. doi:10.1002/anie.200804888 | ||||||||||
Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||||||
ID Code: | 104087 | ||||||||||
Collection: | CaltechAUTHORS | ||||||||||
Deposited By: | George Porter | ||||||||||
Deposited On: | 26 Jun 2020 21:02 | ||||||||||
Last Modified: | 16 Nov 2021 18:28 |
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