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Pachytene piRNAs as beneficial regulators or a defense system gone rogue

Aravin, Alexei A. (2020) Pachytene piRNAs as beneficial regulators or a defense system gone rogue. Nature Genetics, 52 (7). pp. 644-645. ISSN 1061-4036. https://resolver.caltech.edu/CaltechAUTHORS:20200629-132840404

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Abstract

Pachytene Piwi-interacting RNAs (piRNAs) are abundant small non-coding RNAs expressed in mammalian germ lines. A new study indicates that, among the diverse pool of piRNA sequences, a small number act as highly selective guides that induce cleavage of coding and non-coding transcripts, thus promoting piRNA generation and regulating gene expression.


Item Type:Article
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https://doi.org/10.1038/s41588-020-0656-8DOIArticle
https://rdcu.be/b5iZ9PublisherFree ReadCube access
ORCID:
AuthorORCID
Aravin, Alexei A.0000-0002-6956-8257
Additional Information:© 2020 Springer Nature Limited. Published 29 June 2020. The author declares no competing interests.
Funders:
Funding AgencyGrant Number
Howard Hughes Medical Institute (HHMI)UNSPECIFIED
Issue or Number:7
Record Number:CaltechAUTHORS:20200629-132840404
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20200629-132840404
Official Citation:Aravin, A.A. Pachytene piRNAs as beneficial regulators or a defense system gone rogue. Nat Genet 52, 644–645 (2020). https://doi.org/10.1038/s41588-020-0656-8
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:104133
Collection:CaltechAUTHORS
Deposited By: George Porter
Deposited On:29 Jun 2020 20:39
Last Modified:14 Jul 2020 22:23

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