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The Scaling of White Matter to Gray Matter in Cerebellum and Neocortex

Bush, Eliot C. and Allman, John M. (2003) The Scaling of White Matter to Gray Matter in Cerebellum and Neocortex. Brain Behavior And Evolution, 61 (1). pp. 1-5. ISSN 1421-9743. doi:10.1159/000068880.

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It is known that the white matter of neocortex increases disproportionately with brain size. However, relatively few measurements have been made of white matter/gray matter scaling in the cerebellum. We present data on the volumes of white and gray matter in both structures, taken from 45 species of mammals. We find a scaling exponent of 1.13 for cerebellum and 1.28 for neocortex. The 95% confidence intervals for our estimates of these two exponents do not overlap. This difference likely reflects differences in the connectivity and/or micro-structure of white matter in the two regions.

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Additional Information:© 2003 S. Karger AG, Basel. Received: October 3, 2002. Returned for revision: November 1, 2002. Accepted after revision: November 26, 2002. We would like to thank Wally Welker, who provided access to the Wisconsin brain collection, as well as Inge Siggelkow for assistance there. We would also like to thank Sam Wang for several stimulating discussions and for comments and suggestions on a draft of this paper. This work was supported by NIH EY11759 and NIH GM07737.
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Subject Keywords:Mammals | White matter | Cerebellum | Neocortex | Scaling
Issue or Number:1
Record Number:CaltechAUTHORS:20200629-134857201
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:104137
Deposited By: George Porter
Deposited On:29 Jun 2020 21:49
Last Modified:16 Nov 2021 18:28

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