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Cytochrome Oxidase and Functional Coding in Primate Striate Cortex: A Hypothesis

Allman, J. and Zucker, S. (1990) Cytochrome Oxidase and Functional Coding in Primate Striate Cortex: A Hypothesis. Cold Spring Harbor Symposia on Quantitative Biology, 55 . pp. 979-982. ISSN 0091-7451. doi:10.1101/sqb.1990.055.01.092.

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In 1978, Margaret Wong-Riley stained sections of squirrel monkey striate cortex for the activity of the mitochondrial enzyme, cytochrome oxidase, and noticed a periodic distribution of “puffs” of increased enzyme activity in layers 2 and 3 (letter to D. Hubel cited in Livingstone and Hubel [1984]). Her discovery anticipated a whole series of anatomical and physiological findings from many laboratories that correlated with the distribution of this enzyme in the striate cortex of primates, yet there has never been a satisfactory explanation as to why the distribution of this enzyme, crucial for aerobic energy metabolism, would be related to the functional organization of visual cortex (Martin 1988). The puffs have also been called blobs, spots, dots, and patches, with the term blob used most frequently.

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Additional Information:© 1990 by Cold Spring Harbor Laboratory Press. This work was supported by the Hixon Professorship at the California Institute of Technology, the Canadian Institute for Advanced Research, the Air Force Office of Scientific Research, and the Medical Research Council.
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Hixson Professorship, CaltechUNSPECIFIED
Canadian Institute for Advanced Research (CIFAR)UNSPECIFIED
Air Force Office of Scientific Research (AFOSR)UNSPECIFIED
Medical Research Council of CanadaUNSPECIFIED
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Official Citation:Cytochrome Oxidase and Functional Coding in Primate Striate Cortex: A Hypothesis J. Allman and S. Zucker Cold Spring Harb Symp Quant Biol 1990 55: 979-982; doi:10.1101/SQB.1990.055.01.092
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:104144
Deposited By: George Porter
Deposited On:29 Jun 2020 21:04
Last Modified:16 Nov 2021 18:28

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