A Caltech Library Service

Some Aspects of Position Pseudoallelism

Lewis, E. B. (1955) Some Aspects of Position Pseudoallelism. American Naturalist, 89 (845). pp. 73-89. ISSN 0003-0147.

[img] PDF - Published Version
See Usage Policy.


Use this Persistent URL to link to this item:


Contrasting interpretations of position pseudoallelism are discussed, and the types of position effect which characterize this phenomenon are illustrated, with special reference to the case of the bithorax series of five pseudoallelic loci in Drosophila melanogaster. Most of the results in this latter case can be simply interpreted on the basis of a chain of gene-controlled reactions in which each intermediate substance is postulated to act in a dual capacity: as substrate for the succeeding reaction and as a determiner of a specific physiological process. The model also gives a consistent picture of the way in which different levels of developmental determination may be controlled by the different genes of the series.

Item Type:Article
Related URLs:
URLURL TypeDescription
Additional Information:© 1955 University of Chicago Press. Presented at the Symposium on "Pseudoallelism and the theory of the gene" at the annual meeting of The Genetics Society of America, held at Gainesville, Florida, September 11, 1954. This study was aided by a contract with the Atomic Energy Commission (No. 25618).
Funding AgencyGrant Number
Atomic Energy Commission25618
Subject Keywords:Phenotypes; Genetic loci; Chromosomes; Alleles; Drosophila; Insect genetics; Heterozygotes; Homozygotes
Issue or Number:845
Record Number:CaltechAUTHORS:20200717-145827992
Persistent URL:
Official Citation:Lewis, E. B. “Some Aspects of Position Pseudoallelism.” The American Naturalist, vol. 89, no. 845, 1955, pp. 73–89. JSTOR, Accessed 17 July 2020
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:104432
Deposited By: Tony Diaz
Deposited On:17 Jul 2020 22:07
Last Modified:17 Jul 2020 22:07

Repository Staff Only: item control page