Lewis, E. B. (1955) Some Aspects of Position Pseudoallelism. American Naturalist, 89 (845). pp. 73-89. ISSN 0003-0147. https://resolver.caltech.edu/CaltechAUTHORS:20200717-145827992
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Abstract
Contrasting interpretations of position pseudoallelism are discussed, and the types of position effect which characterize this phenomenon are illustrated, with special reference to the case of the bithorax series of five pseudoallelic loci in Drosophila melanogaster. Most of the results in this latter case can be simply interpreted on the basis of a chain of gene-controlled reactions in which each intermediate substance is postulated to act in a dual capacity: as substrate for the succeeding reaction and as a determiner of a specific physiological process. The model also gives a consistent picture of the way in which different levels of developmental determination may be controlled by the different genes of the series.
Item Type: | Article | ||||||
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Additional Information: | © 1955 University of Chicago Press. Presented at the Symposium on "Pseudoallelism and the theory of the gene" at the annual meeting of The Genetics Society of America, held at Gainesville, Florida, September 11, 1954. This study was aided by a contract with the Atomic Energy Commission (No. 25618). | ||||||
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Subject Keywords: | Phenotypes; Genetic loci; Chromosomes; Alleles; Drosophila; Insect genetics; Heterozygotes; Homozygotes | ||||||
Issue or Number: | 845 | ||||||
Record Number: | CaltechAUTHORS:20200717-145827992 | ||||||
Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20200717-145827992 | ||||||
Official Citation: | Lewis, E. B. “Some Aspects of Position Pseudoallelism.” The American Naturalist, vol. 89, no. 845, 1955, pp. 73–89. JSTOR, www.jstor.org/stable/2458694. Accessed 17 July 2020 | ||||||
Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||
ID Code: | 104432 | ||||||
Collection: | CaltechAUTHORS | ||||||
Deposited By: | Tony Diaz | ||||||
Deposited On: | 17 Jul 2020 22:07 | ||||||
Last Modified: | 17 Jul 2020 22:07 |
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