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Three-dimensional structure and evolution of primate primary visual cortex

Bush, Eliot C. and Allman, John M. (2004) Three-dimensional structure and evolution of primate primary visual cortex. The Anatomical Record, 281A (1). pp. 1088-1094. ISSN 0003-276X. doi:10.1002/ar.a.20114.

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In this study, three-dimensional reconstructions of primate primary visual cortex (V1) were used to address questions about its evolution. The three-dimensional shape of V1 in anthropoids is significantly longer and narrower than in strepsirrhines. This difference is an effect of clade and is not due to differences in activity pattern or V1 size. New measurements of V1 volume were also provided in order to reassess V1 size differences between strepsirrhines and anthropoids. It was found that for a given lateral geniculate nucleus (LGN) volume, anthropoids have a significantly larger V1 than strepsirrhines do. This is important since LGN is the principal source of V1’s input. Finally, independent contrasts analysis was used to examine the scaling of V1 relative to LGN, the rest of cortex, and the rest of the brain. It was confirmed that V1 scales with positive allometry relative to LGN. A number of possible explanations for scaling are discussed. V1 scaling may have to do with the tendency of large brains to be more compartmentalized than small brains, or V1 scaling might reflect the geometry of information representation.

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Additional Information:© 2004 Wiley-Liss, Inc. Issue Online: 19 October 2004. Version of Record online: 06 October 2004. Manuscript accepted: 01 July 2004. Manuscript received: 20 May 2004. Grant sponsor: the National Institutes of Health; Grant number: EY11759; Grant sponsor: W.M. Keck Foundation for Discovery in Basic Medical Research at the California Institute of Technology. The authors thank Wally Welker, Inge Siggelkow, and Archie Fobbs for access to the Wisconsin brain collection and Kebreten Manaye for use of her Stereo Investigator.
Funding AgencyGrant Number
W. M. Keck FoundationUNSPECIFIED
Subject Keywords:allometry; horizontal meridian; independent contrasts
Issue or Number:1
Record Number:CaltechAUTHORS:20200720-124523596
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Official Citation:Bush, E.C. and Allman, J.M. (2004), Three‐dimensional structure and evolution of primate primary visual cortex. Anat. Rec., 281A: 1088-1094. doi:10.1002/ar.a.20114
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:104452
Deposited By: Rebecca Minjarez
Deposited On:22 Jul 2020 17:00
Last Modified:16 Nov 2021 18:31

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