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Coupling of polyoma DNA and RNA synthesis

Glover, D. M. (1974) Coupling of polyoma DNA and RNA synthesis. Biochemical and Biophysical Research Communications, 57 (4). pp. 1137-1143. ISSN 0006-291X. doi:10.1016/0006-291x(74)90815-8.

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Polyoma virus RNA from infected mouse embryo cells was examined by gel electrophoresis and in nucleic acid hybridisation experiments. The extent of representation of the polyoma genome in RNA sequences when cytosine arabinoside is present throughout infection is 30 to 40% of that at late times in infection. When viral DNA synthesis is inhibited during the period in which it is rising to its maximum, the resulting cytoplasmic RNA resembles ‘early’ RNA both in size and by its behaviour in competition hybridisation experiments.

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Glover, D. M.0000-0003-0956-0103
Additional Information:© 1974 Academic Press. Received 5 March 1974. This work fufils part of the requirements for the degree of Ph. D. London University, 1972. The author would like to thank Drs. R. Laskey W. Folk and L. Crawford for advice and criticism.
Issue or Number:4
Record Number:CaltechAUTHORS:20200806-163116783
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Official Citation:D.M. Glover, Coupling of polyoma DNA and RNA synthesis, Biochemical and Biophysical Research Communications, Volume 57, Issue 4, 1974, Pages 1137-1143, ISSN 0006-291X,
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:104799
Deposited By: George Porter
Deposited On:10 Aug 2020 17:44
Last Modified:16 Nov 2021 18:35

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