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Coupling of polyoma DNA and RNA synthesis

Glover, D. M. (1974) Coupling of polyoma DNA and RNA synthesis. Biochemical and Biophysical Research Communications, 57 (4). pp. 1137-1143. ISSN 0006-291X. https://resolver.caltech.edu/CaltechAUTHORS:20200806-163116783

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Abstract

Polyoma virus RNA from infected mouse embryo cells was examined by gel electrophoresis and in nucleic acid hybridisation experiments. The extent of representation of the polyoma genome in RNA sequences when cytosine arabinoside is present throughout infection is 30 to 40% of that at late times in infection. When viral DNA synthesis is inhibited during the period in which it is rising to its maximum, the resulting cytoplasmic RNA resembles ‘early’ RNA both in size and by its behaviour in competition hybridisation experiments.


Item Type:Article
Related URLs:
URLURL TypeDescription
https://doi.org/10.1016/0006-291x(74)90815-8DOIArticle
ORCID:
AuthorORCID
Glover, D. M.0000-0003-0956-0103
Additional Information:© 1974 Academic Press. Received 5 March 1974. This work fufils part of the requirements for the degree of Ph. D. London University, 1972. The author would like to thank Drs. R. Laskey W. Folk and L. Crawford for advice and criticism.
Issue or Number:4
Record Number:CaltechAUTHORS:20200806-163116783
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20200806-163116783
Official Citation:D.M. Glover, Coupling of polyoma DNA and RNA synthesis, Biochemical and Biophysical Research Communications, Volume 57, Issue 4, 1974, Pages 1137-1143, ISSN 0006-291X, https://doi.org/10.1016/0006-291X(74)90815-8.
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:104799
Collection:CaltechAUTHORS
Deposited By: George Porter
Deposited On:10 Aug 2020 17:44
Last Modified:10 Aug 2020 17:44

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