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Transcription of the ‘non-transcribed’ spacer of Drosophila melanogaster rDNA

Miller, J. Ross and Hayward, David C. and Glover, David M. (1983) Transcription of the ‘non-transcribed’ spacer of Drosophila melanogaster rDNA. Nucleic Acids Research, 11 (1). pp. 11-19. ISSN 0305-1048. PMCID PMC325687. doi:10.1093/nar/11.1.11.

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We have detected a set of transcripts in Drosophila melanogaster cells which are homologous to repeating elements within the ‘non-transcribed’ spacer region of rDNA. The RNA molecules range from 240 to 1680 nucleotides, differing in length by an integral value of 240 nucleotides. We have sequenced several AluI fragments which characterise the main 240 nucleotide repeating element. We find that each of these fragments contain a segment of approximately 50 nucleotides, which is homologous to the transcription initiation site for pre-rRNA.

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Glover, David M.0000-0003-0956-0103
Additional Information:© 1983 IRL Press. Creative Commons Attribution Non-Commercial licence (CC BY-NC). Received 17 November 1982; Revised and Accepted 9 December 1982. This work was supported by an MRC project grant. DMG holds a career development award from the Cancer Research Campaign. The Imperial Cancer Research Fund generously made their computing facilities available to us.
Funding AgencyGrant Number
Medical Research Council (UK)UNSPECIFIED
Cancer Research CampaignUNSPECIFIED
Imperial Cancer Research FundUNSPECIFIED
Issue or Number:1
PubMed Central ID:PMC325687
Record Number:CaltechAUTHORS:20200807-170350833
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Official Citation:J. Ross Miller, David C. Hayward, David M. Glover, Transcription of the ‘non-transcribed’ spacer of Drosophila melanogaster rDNA, Nucleic Acids Research, Volume 11, Issue 1, 11 January 1983, Pages 11–19,
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:104841
Deposited By: George Porter
Deposited On:11 Aug 2020 17:33
Last Modified:16 Nov 2021 18:36

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