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New players on the piRNA field

Ninova, Maria and Fejes Tóth, Katalin (2020) New players on the piRNA field. Nature Structural & Molecular Biology, 27 (9). pp. 771-779. ISSN 1545-9993.

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The nuclear piRNA pathway safeguards genome integrity in the germline by silencing transposable elements. Three recent studies have identified new players in the mammalian pathway. Two of these, TEX15 and SPOCD1, might provide a link between piRNA-guided complexes that recognize genomic targets and the molecular machinery that induces DNA methylation and transcriptional repression during mouse spermatogenesis.

Item Type:Article
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Ninova, Maria0000-0001-5051-5502
Fejes Tóth, Katalin0000-0001-6558-2636
Additional Information:© 2020 Nature Publishing Group. Published: 12 August 2020; Issue Date: September 2020. The authors declare no competing interests.
Subject Keywords:DNA methylation; Gene silencing; Piwi RNAs
Issue or Number:9
Record Number:CaltechAUTHORS:20200812-120210398
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Official Citation:Ninova, M., Fejes Tóth, K. New players on the piRNA field. Nat Struct Mol Biol 27, 777–779 (2020).
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:104931
Deposited By: Tony Diaz
Deposited On:12 Aug 2020 20:48
Last Modified:16 Nov 2020 22:30

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