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New players on the piRNA field

Ninova, Maria and Fejes Tóth, Katalin (2020) New players on the piRNA field. Nature Structural & Molecular Biology, 27 (9). pp. 771-779. ISSN 1545-9993. https://resolver.caltech.edu/CaltechAUTHORS:20200812-120210398

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Abstract

The nuclear piRNA pathway safeguards genome integrity in the germline by silencing transposable elements. Three recent studies have identified new players in the mammalian pathway. Two of these, TEX15 and SPOCD1, might provide a link between piRNA-guided complexes that recognize genomic targets and the molecular machinery that induces DNA methylation and transcriptional repression during mouse spermatogenesis.


Item Type:Article
Related URLs:
URLURL TypeDescription
https://doi.org/10.1038/s41594-020-0484-7DOIArticle
https://rdcu.be/b6dVuPublisherFree ReadCube access
ORCID:
AuthorORCID
Ninova, Maria0000-0001-5051-5502
Fejes Tóth, Katalin0000-0001-6558-2636
Additional Information:© 2020 Nature Publishing Group. Published: 12 August 2020; Issue Date: September 2020. The authors declare no competing interests.
Subject Keywords:DNA methylation; Gene silencing; Piwi RNAs
Issue or Number:9
Record Number:CaltechAUTHORS:20200812-120210398
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20200812-120210398
Official Citation:Ninova, M., Fejes Tóth, K. New players on the piRNA field. Nat Struct Mol Biol 27, 777–779 (2020). https://doi.org/10.1038/s41594-020-0484-7
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:104931
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:12 Aug 2020 20:48
Last Modified:16 Nov 2020 22:30

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