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Illuminating the core of adaptive immunity—how the regulatory genome controls Rag chromatin dynamics

Wang, Xun and Rothenberg, Ellen V. (2020) Illuminating the core of adaptive immunity—how the regulatory genome controls Rag chromatin dynamics. Science Immunology, 5 (51). Art. No. eabd6427. ISSN 2470-9468. https://resolver.caltech.edu/CaltechAUTHORS:20200909-142850654

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Abstract

E2A specifies adaptive immunity by instructing large-scale topological changes for Rag gene super-enhancer formation (see the related Research Article by Miyazaki et al.).


Item Type:Article
Related URLs:
URLURL TypeDescription
https://doi.org/10.1126/sciimmunol.abd6427DOIArticle
https://doi.org/10.1126/sciimmunol.abb1455DOIMiyazaki et al.
ORCID:
AuthorORCID
Wang, Xun0000-0002-1653-5750
Rothenberg, Ellen V.0000-0002-3901-347X
Additional Information:© 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. The authors were supported by USPHS grants R01AI135200 and R01HD100039, with support from the Division of Biology & Biological Engineering Bowes Leadership Chair Fund (X.W.), and by the A. B. Ruddock Professorship (E.V.R.).
Funders:
Funding AgencyGrant Number
NIHR01AI135200
NIHR01HD100039
Caltech Division of Biology and Biological EngineeringUNSPECIFIED
Albert Billings Ruddock ProfessorshipUNSPECIFIED
Issue or Number:51
Record Number:CaltechAUTHORS:20200909-142850654
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20200909-142850654
Official Citation:X. Wang, E. V. Rothenberg, Illuminating the core of adaptive immunity—how the regulatory genome controls Rag chromatin dynamics. Sci. Immunol. 5, eabd6427 (2020).
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:105300
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:09 Sep 2020 21:48
Last Modified:09 Sep 2020 21:48

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