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Neurophysiological defects in temperature-sensitive paralytic mutants of Drosophila melanogaster

Siddiqi, Obaid and Benzer, Seymour (1976) Neurophysiological defects in temperature-sensitive paralytic mutants of Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America, 73 (9). pp. 3253-3257. ISSN 0027-8424. PMCID PMC430996. https://resolver.caltech.edu/CaltechAUTHORS:SIDpnas76

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Abstract

A new temperature-sensitive paralytic mutant of Drosophila, comatose, is compared behaviorally and physiologically with the previously known types, para and shi. All three have different properties with respect to kinetics of paralysis at high temperature and recovery from paralysis; com is hypersensitive to paralysis by cooling. Neurophysiological experiments indicate different mechanisms for paralysis in each of the mutants.


Item Type:Article
Related URLs:
URLURL TypeDescription
https://doi.org/10.1073/pnas.73.9.3253DOIArticle
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC430996/PubMed CentralArticle
http://www.pnas.org/cgi/content/abstract/73/9/3253OtherUNSPECIFIED
http://www.pnas.org/cgi/content/abstract/73/9/3253OtherUNSPECIFIED
Additional Information:© 1976 by the National Academy of Sciences. Contributed by Seymour Benzer, July 6, 1976. We acknowledge the excellent technical assistance of Paul Christensen. This research was supported by Grant no. PCM 73-01972 from the National Science Foundation to S.B. and by a Gosney Research Fellowship to O.S.
Funders:
Funding AgencyGrant Number
NSFPCM 73-01972
Gosney FoundationUNSPECIFIED
Subject Keywords:neurogenetics; neuromuscular junction; behavioral mutants
Issue or Number:9
PubMed Central ID:PMC430996
Record Number:CaltechAUTHORS:SIDpnas76
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:SIDpnas76
Official Citation:Neurophysiological defects in temperature-sensitive paralytic mutants of Drosophila melanogaster O Siddiqi, S Benzer Proceedings of the National Academy of Sciences Sep 1976, 73 (9) 3253-3257; DOI: 10.1073/pnas.73.9.3253
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:10550
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:17 May 2008
Last Modified:03 Oct 2019 00:10

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