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Neurophysiological defects in temperature-sensitive paralytic mutants of Drosophila melanogaster

Siddiqi, Obaid and Benzer, Seymour (1976) Neurophysiological defects in temperature-sensitive paralytic mutants of Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America, 73 (9). pp. 3253-3257. ISSN 0027-8424.

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A new temperature-sensitive paralytic mutant of Drosophila, comatose, is compared behaviorally and physiologically with the previously known types, para and shi. All three have different properties with respect to kinetics of paralysis at high temperature and recovery from paralysis; com is hypersensitive to paralysis by cooling. Neurophysiological experiments indicate different mechanisms for paralysis in each of the mutants.

Item Type:Article
Additional Information:© 1976 by the National Academy of Sciences. Contributed by Seymour Benzer, July 6, 1976. We acknowledge the excellent technical assistance of Paul Christensen. This research was supported by Grant no. PCM 73-01972 from the National Science Foundation to S.B. and by a Gosney Research Fellowship to O.S.
Subject Keywords:neurogenetics; neuromuscular junction; behavioral mutants
Record Number:CaltechAUTHORS:SIDpnas76
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:10550
Deposited By: Tony Diaz
Deposited On:17 May 2008
Last Modified:14 Nov 2014 19:20

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