Glover, David M. (2003) Aurora A on the Mitotic Spindle Is Activated by the Way It Holds Its Partner. Molecular Cell, 12 (4). pp. 797-799. ISSN 1097-2765. doi:10.1016/s1097-2765(03)00405-2. https://resolver.caltech.edu/CaltechAUTHORS:20200928-150626522
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Abstract
An exciting study in this issue (Bayliss et al., 2003) reveals how binding of the microtubule associated protein TPX2 to the mitotic kinase Aurora A induces a conformational change. This moves the phosphorylated activation domain into a more compact position within the kinase core, providing a better substrate binding platform and hiding the activating phosphoryl group from attack by PP1.
| Item Type: | Article | ||||||
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| Additional Information: | © 2003 Cell Press. Under an Elsevier user license. | ||||||
| Issue or Number: | 4 | ||||||
| DOI: | 10.1016/s1097-2765(03)00405-2 | ||||||
| Record Number: | CaltechAUTHORS:20200928-150626522 | ||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20200928-150626522 | ||||||
| Official Citation: | David M Glover, Aurora A on the Mitotic Spindle Is Activated by the Way It Holds Its Partner, Molecular Cell, Volume 12, Issue 4, 2003, Pages 797-799, ISSN 1097-2765, https://doi.org/10.1016/S1097-2765(03)00405-2. | ||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||
| ID Code: | 105614 | ||||||
| Collection: | CaltechAUTHORS | ||||||
| Deposited By: | George Porter | ||||||
| Deposited On: | 29 Sep 2020 15:56 | ||||||
| Last Modified: | 16 Nov 2021 18:44 |
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