CaltechAUTHORS
  A Caltech Library Service

5.8 S and 2 S rDNA is located in the ‘transcribed spacer’ region between the 18 S and 26 S rRNA genes in Drosophila melanogaster

Jordan, Bertrand R. and Glover, David M. (1977) 5.8 S and 2 S rDNA is located in the ‘transcribed spacer’ region between the 18 S and 26 S rRNA genes in Drosophila melanogaster. FEBS Letters, 78 (2). pp. 271-274. ISSN 0014-5793. https://resolver.caltech.edu/CaltechAUTHORS:20200928-150626940

Full text is not posted in this repository. Consult Related URLs below.

Use this Persistent URL to link to this item: https://resolver.caltech.edu/CaltechAUTHORS:20200928-150626940

Abstract

In Drosophila melanogaster, two small RNA species are found hydrogen bonded to 26 S rRNA:5.8 S rRNA, approximately 125 nucleotides long, and 2 S rRNA, 30 nucleotides long [1]. Evidence from pulse-chase experiments shows that they arise as the result of post transcriptional processing of 26 S RNA, and that the corresponding cleavages occur in the cytoplasm after the central cleavage of the 26 S molecule which occurs in the nucleus [1]. These results do not define completely the architecture of the 26 S molecule and a number of different models remain possible (fig.1). If it is assumed, by analogy with Xenopus laevis [2] that 5.8 S rRNA is coded by a DNA region located between the genes for 18 S and 26 S rRNAs, then class (c) models can be excluded. The experiments reported here examine this question directly by hybridization of ³²P-1abelled 5.8 S and 2 S RNAs to cloned D. melanogaster rDNA fragments [3].


Item Type:Article
Related URLs:
URLURL TypeDescription
https://doi.org/10.1016/0014-5793(77)80321-9DOIArticle
ORCID:
AuthorORCID
Glover, David M.0000-0003-0956-0103
Additional Information:© 1977 Federation of European Biochemical Societies. Received 1 April 1977. This work was supported by a Medical Research Council grant to D.M.G. and by grants from the Commissariat à l’Energie Atomique and the Centre National de la Recherche Scientifique to B.R.J. B.R.J. is also grateful for a short term EMBO fellowship which enabled him to work at Imperial College, London.
Funders:
Funding AgencyGrant Number
Medical Research Council (UK)UNSPECIFIED
Commissariat à l’Energie Atomique (CEA)UNSPECIFIED
Centre National de la Recherche Scientifique (CNRS)UNSPECIFIED
European Molecular Biology Organization (EMBO)UNSPECIFIED
Issue or Number:2
Record Number:CaltechAUTHORS:20200928-150626940
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20200928-150626940
Official Citation:Jordan, Bertrand R. & Glover, David M. (1977), 5.8 S and 2 S rDNA is located in the ‘transcribed spacer’ region between the 18 S and 26 S rRNA genes in Drosophila melanogaster, FEBS Letters, 78, doi: 10.1016/0014-5793(77)80321-9
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:105618
Collection:CaltechAUTHORS
Deposited By: George Porter
Deposited On:28 Sep 2020 22:33
Last Modified:28 Sep 2020 22:34

Repository Staff Only: item control page