CaltechAUTHORS
  A Caltech Library Service

Electrophysiological Experiments With Photoisomerizable Cholinergic Compounds: Review and Progress Report

Lester, Henry A. and Nass, Menasche M. and Krouse, Mauri E. and Nerbonne, Jeanne M. and Wassermann, Norbert H. and Erlanger, Bernard F. (1980) Electrophysiological Experiments With Photoisomerizable Cholinergic Compounds: Review and Progress Report. Annals of the New York Academy of Sciences, 346 . pp. 475-490. ISSN 0077-8923. doi:10.1111/j.1749-6632.1980.tb22118.x. https://resolver.caltech.edu/CaltechAUTHORS:20201005-113706477

Full text is not posted in this repository. Consult Related URLs below.

Use this Persistent URL to link to this item: https://resolver.caltech.edu/CaltechAUTHORS:20201005-113706477

Abstract

Many small molecules, both natural and synthetic, act on biological membranes by controlling ionic channels in the membrane. Our particular interest is the channel associated with the acetylcholine receptor in the postsynaptic membrane of the nicotinic synapse, where impulses are transferred from a nerve to a muscle fiber or (in some fishes) to an electroplaque. This synapse is a highly efficient electrochemical machine, specialized to function on a millisecond time scale. The immediate challenge is to understand the electrical and chemical regulation of receptor channels on this same time scale.


Item Type:Article
Related URLs:
URLURL TypeDescription
https://doi.org/10.1111/j.1749-6632.1980.tb22118.xDOIArticle
ORCID:
AuthorORCID
Lester, Henry A.0000-0002-5470-5255
Additional Information:© 1980, NYAS. This research was supported by the Muscular Dystrophy Association (fellowship to M.M.N. and grant‐in‐aid), by the National Institutes of Health (fellowship to J.M.N., RCDA NS‐272 to H.A.L., and grant no. NS‐11756), and by the National Science Foundation (grant no. PCM‐74‐02140).
Funders:
Funding AgencyGrant Number
Muscular Dystrophy AssociationUNSPECIFIED
NIH Predoctoral FellowshipUNSPECIFIED
NIHNS‐272
NIHNS‐11756
NSFPCM 74‐02140
DOI:10.1111/j.1749-6632.1980.tb22118.x
Record Number:CaltechAUTHORS:20201005-113706477
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20201005-113706477
Official Citation:Lester, H.A., Nass, M.M., Krouse, M.E., Nerbonne, J.M., Wassermann, N.H. and Erlanger, B.F. (1980), Electrophysiological Experiments With Photoisomerizable Cholinergic Compounds: Review and Progress Report. Annals of the New York Academy of Sciences, 346: 475-490. doi:10.1111/j.1749-6632.1980.tb22118.x
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:105802
Collection:CaltechAUTHORS
Deposited By: George Porter
Deposited On:05 Oct 2020 19:26
Last Modified:16 Nov 2021 18:46

Repository Staff Only: item control page