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Activation and Densensitization in Bacterial Chemotaxis

Simon, Melvin I. (1990) Activation and Densensitization in Bacterial Chemotaxis. In: Activation and Desensitization of Transducing Pathways. NATO ASI Series. Series F. No.44. Springer Berlin Heidelberg , Berlin, Heidelberg, pp. 3-21. ISBN 9783642836206.

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Bacterial chemotaxis allows cells to respond to over 35 different There are transmembrane cell surface The bound state of the receptor intracellular protein kinase that can phosphorylate two chemotaxis system components, the CheY and the CheB proteins. When CheY is phosphorylated it modulates bacterial flagellar rotation and thus effects the cells’ movement. When CheB is phosphorylated it increases its ability to modify the cell surface receptor and change its sensitivity. A model for the integration of these steps into a scheme that can explain the dynamic range, rapid response and sensitivity of the bacterial sensory system is described. This represents one example of a much larger group of “two component” sensory systems in bacteria.

Item Type:Book Section
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Additional Information:© Springer-Verlag Berlin Heidelberg 1990.
Subject Keywords:Signal transduction; Chemotaxis; protein kinase; transphosphorylation
Series Name:NATO ASI Series. Series F
Issue or Number:44
Record Number:CaltechAUTHORS:20201008-131242087
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:105933
Deposited By: George Porter
Deposited On:09 Oct 2020 14:18
Last Modified:16 Nov 2021 18:47

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