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The major serum protein of Drosophila larvae, larval serum protein 1, is dispensable

Roberts, David B. and Jowett, Trevor and Hughes, Jane and Smith, Deborah F. and Glover, David M. (1991) The major serum protein of Drosophila larvae, larval serum protein 1, is dispensable. European Journal of Biochemistry, 195 (1). pp. 195-201. ISSN 0014-2956. doi:10.1111/j.1432-1033.1991.tb15695.x. https://resolver.caltech.edu/CaltechAUTHORS:20201013-133531975

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Abstract

Null alleles of all three genes (α, β and γ) coding for the major serum protein of Drosophila larvae, larval serum protein 1, have been characterized at the protein level and by analysis of their RNA and DNA. Each allele completely lacks one polypeptide chain. β° shows an unaltered gene but reduced levels of RNA, α° shows restriction‐fragment‐length polymorphism and shows low levels of transcript, while γ° is a deletion. The three null alleles have been combined to give a strain without the gene for larval serum protein 1 which survives


Item Type:Article
Related URLs:
URLURL TypeDescription
https://doi.org/10.1111/j.1432-1033.1991.tb15695.xDOIArticle
ORCID:
AuthorORCID
Glover, David M.0000-0003-0956-0103
Additional Information:© FEBS 1991. (Received August 23, 1990) We would like to acknowledge, once again, our debt of gratitude to Jean Matthews for feeding the flies. The work was supported by a grant from the Science and Engineering Research Council to DBR and a grant from the Clinical Research Council to DS and DG.
Funders:
Funding AgencyGrant Number
Science and Engineering Research Council (SERC)UNSPECIFIED
Clinical Research CouncilUNSPECIFIED
Issue or Number:1
DOI:10.1111/j.1432-1033.1991.tb15695.x
Record Number:CaltechAUTHORS:20201013-133531975
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20201013-133531975
Official Citation:ROBERTS, D.B., JOWETT, T., HUGHES, J., SMITH, D.F. and GLOVER, D.M. (1991), The major serum protein of Drosophila larvae, larval serum protein 1, is dispensable. European Journal of Biochemistry, 195: 195-201. doi:10.1111/j.1432-1033.1991.tb15695.x
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:106032
Collection:CaltechAUTHORS
Deposited By: George Porter
Deposited On:13 Oct 2020 21:55
Last Modified:16 Nov 2021 18:49

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