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Expression of mRNA Encoding Rat Brain Ca²⁺ Channels in Xenopus Oocytes

Lester, H. A. and Snutch, T. P. and Leonard, J. P. and Nargeot, J. and Davidson, N. (1988) Expression of mRNA Encoding Rat Brain Ca²⁺ Channels in Xenopus Oocytes. In: The Calcium Channel: Structure, Function and Implications. Bayer AG Centenary Symposium. Springer Berlin Heidelberg , Berlin, Heidelberg, pp. 272-280. ISBN 9783540500612.

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Our laboratory is seeking a mechanistic picture of the action of the voltage-dependent, Ca²⁺-selective ion channels that partially underlie the electrical excitability of membranes. Full explanations will ultimately require pictures of such molecules at atomic resolution (as obtained with X-ray crystallography) in all their states (closed, open, inactivated, etc.). Such structural information is not yet available for any channel.

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Lester, H. A.0000-0002-5470-5255
Alternate Title:Expression of mRNA Encoding Rat Brain Ca2+ Channels in Xenopus Oocytes
Additional Information:© Springer-Verlag Berlin Heidelberg 1988. This research was sponsored by grants from the National Institutes of Health (GM-10991 and GM-29836), and by postdoctoral fellowships from the American Heart Association to T. P. S. J. P. L. and J.N. thanks Laboratoire Servier for a travel grant.
Funding AgencyGrant Number
American Heart AssociationUNSPECIFIED
Laboratoire ServierUNSPECIFIED
Subject Keywords:Xenopus Oocyte; Electrical Excitability; Macroscopic Current; Muscle Acetylcholine Receptor; Phorbol Ester Stimulation
Series Name:Bayer AG Centenary Symposium
Record Number:CaltechAUTHORS:20201014-153713952
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:106073
Deposited By: George Porter
Deposited On:14 Oct 2020 22:46
Last Modified:16 Nov 2021 18:49

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