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Molecular Models of Amino Acids, Peptides, and Proteins

Corey, Robert B. and Pauling, Linus (1953) Molecular Models of Amino Acids, Peptides, and Proteins. Review of Scientific Instruments, 24 (8). pp. 621-627. ISSN 0034-6748. doi:10.1063/1.1770803. https://resolver.caltech.edu/CaltechAUTHORS:20201022-105318967

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Abstract

A set of accurate scale models has been developed for use in studies of the structures of amino acids, peptides, and proteins. Models representing atoms or groups of atoms built from hard wood to the scale 1 in.=1A are connected by a clamping device which maintains desired molecular configurations. These accurate models have been used as substitutes for calculation in investigations of the probable configuration of the polypeptide chain in proteins. Analogous models constructed of rubber‐like plastic to the scale 1 in.=2A and connected by snap fasteners are designed for qualitative studies of protein structure.


Item Type:Article
Related URLs:
URLURL TypeDescription
https://doi.org/10.1063/1.1770803DOIArticle
Additional Information:© 1953 American Institute of Physics. (Received August 25, 1952) Aided by a grant from the National Foundation for Infantile Paralysis. The development of the molecular models described in this paper has been a collaborative effort in which many members of the staff of the California Institute of Technology have participated. We are especially grateful to Roger Hayward and William W. Schuelke for their ingenious solutions of many of the problems of design and construction, to Delmer D. Dill for his excellent workmanship, and to many members of the Institute faculty for their criticisms and suggestions. For five years this work was aided by a grant from the National Foundation for Infantile Paralysis; more recently it has been aided by a grant from the National Institutes of Health, U. S. Public Health Service.
Funders:
Funding AgencyGrant Number
National Foundation for Infantile ParalysisUNSPECIFIED
NIHUNSPECIFIED
Other Numbering System:
Other Numbering System NameOther Numbering System ID
Gates and Crellin Laboratories of Chemistry1731
Issue or Number:8
DOI:10.1063/1.1770803
Record Number:CaltechAUTHORS:20201022-105318967
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20201022-105318967
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:106222
Collection:CaltechAUTHORS
Deposited By: George Porter
Deposited On:22 Oct 2020 19:32
Last Modified:16 Nov 2021 18:52

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