A multimodal cell census and atlas of the mammalian primary motor cortex

Adkins, Ricky S. and Aldridge, Andrew I. and Allen, Shona and Ament, Seth A. and An, Xu and Armand, Ethan and Ascoli, Giorgio A. and Bakken, Trygve E. and Bandrowski, Anita and Banerjee, Samik and Barkas, Nikolaos and Bartlett, Anna and Bateup, Helen S. and Behrens, M. Margarita and Berens, Philipp and Berg, Jim and Bernabucci, Matteo and Bernaerts, Yves and Bertagnolli, Darren and Biancalani, Tommaso and Boggeman, Lara and Booeshaghi, A. Sina and Bowman, Ian and Bravo, Héctor Corrada and Cadwell, Cathryn René and Callaway, Edward M. and Carlin, Benjamin and O'Connor, Carolyn and Carter, Robert and Casper, Tamara and Castanon, Rosa G. and Castro, Jesus Ramon and Chance, Rebecca K. and Chatterjee, Apaala and Chen, Huaming and Chun, Jerold and Colantuoni, Carlo and Crabtree, Jonathan and Creasy, Heather and Crichton, Kirsten and Crow, Megan and D'Orazi, Florence D. and Daigle, Tanya L. and Dalley, Rachel and Dee, Nick and Degatano, Kylee and Dichter, Benjamin and Diep, Dinh and Ding, Liya and Ding, Song-Lin and Dominguez, Bertha and Dong, Hong-Wei and Dong, Weixiu and Dougherty, Elizabeth L. and Dudoit, Sandrine and Ecker, Joseph R. and Eichhorn, Stephen W. and Fang, Rongxin and Felix, Victor and Feng, Guoping and Feng, Zhao and Fischer, Stephan and Fitzpatrick, Conor and Fong, Olivia and Foster, Nicholas N. and Galbavy, William and Gee, James C. and Ghosh, Satrajit S. and Giglio, Michelle and Gillespie, Thomas H. and Gillis, Jesse and Goldman, Melissa and Goldy, Jeff and Gong, Hui and Gou, Lin and Grauer, Michael and Halchenko, Yaroslav O. and Harris, Julie A. and Hartmanis, Leonard and Hatfield, Joshua T. and Hawrylycz, Mike and Helba, Brian and Herb, Brian R. and Hertzano, Ronna and Hintiryan, Houri and Hirokawa, Karla E. and Hockemeyer, Dirk and Hodge, Rebecca D. and Hood, Greg and Horwitz, Gregory D. and Hou, Xiaomeng and Hu, Lijuan and Hu, Qiwen and Huang, Z. Josh and Huo, Bingxing and Ito-Cole, Tony and Jacobs, Matthew and Jia, Xueyan and Jiang, Shengdian and Jiang, Tao and Jiang, Xiaolong and Jin, Xin and Jorstad, Nikolas L. and Kalmbach, Brian E. and Kancherla, Jayaram and Keene, C. Dirk and Kelly, Kathleen and Khajouei, Farzaneh and Kharchenko, Peter V. and Kim, Gukhan and Ko, Andrew L. and Kobak, Dmitry and Konwar, Kishori and Kramer, Daniel J. and Krienen, Fenna M. and Kroll, Matthew and Kuang, Xiuli and Kuo, Hsien-Chi and Lake, Blue B. and Larsen, Rachael and Lathia, Kanan and Laturnus, Sophie and Lee, Angus Y. and Lee, Cheng-Ta and Lee, Kuo-Fen and Lein, Ed S. and Lesnar, Phil and Li, Anan and Li, Xiangning and Li, Xu and Li, Yang Eric and Li, Yaoyao and Li, Yuanyuan and Lim, Byungkook and Linnarsson, Sten and Liu, Christine S. and Liu, Hanqing and Liu, Lijuan and Lucero, Jacinta D. and Luo, Chongyuan and Luo, Qingming and Macosko, Evan Z. and Mahurkar, Anup and Martone, Maryann E. and Matho, Katherine S. and McCarroll, Steven A. and McCracken, Carrie and McMillen, Delissa and Miranda, Elanine and Mitra, Partha P and Miyazaki, Paula Assakura and Mizrachi, Judith and Mok, Stephanie and Mukamel, Eran A. and Mulherkar, Shalaka and Nadaf, Naeem M. and Naeemi, Maitham and Narasimhan, Arun and Nery, Joseph R. and Ng, Lydia and Ngai, John and Nguyen, Thuc Nghi and Nickel, Lance and Nicovich, Philip R. and Niu, Sheng-Yong and Ntranos, Vasilis and Nunn, Michael and Olley, Dustin and Orvis, Joshua and Osteen, Julia K. and Osten, Pavel and Owen, Scott F. and Pachter, Lior and Palaniswamy, Ramesh and Palmer, Carter R. and Pang, Yan and Peng, Hanchuan and Pham, Thanh and Pinto-Duarte, Antonio and Plongthongkum, Nongluk and Poirion, Olivier and Preissl, Sebastian and Purdom, Elizabeth and Qu, Lei and Rashid, Mohammad and Reed, Nora M. and Regev, Aviv and Ren, Bing and Ren, Miao and Rimorin, Christine and Risso, Davide and Rivkin, Angeline C. and Muñoz-Castañeda, Rodrigo and Romanow, William J. and Ropelewski, Alexander J. and Roux de Bézieux, Hector and Ruan, Zongcai and Sandberg, Rickard and Savoia, Steven and Scala, Federico and Schor, Michael and Shen, Elise and Siletti, Kimberly and Smith, Jared B. and Smith, Kimberly and Somasundaram, Saroja and Song, Yuanyuan and Sorensen, Staci A. and Stafford, David A. and Street, Kelly and Sulc, Josef and Sunkin, Susan and Svensson, Valentine and Tan, Pengcheng and Tan, Zheng Huan and Tasic, Bosiljka and Thompson, Carol and Tian, Wei and Tickle, Timothy L. and Tieu, Michael and Ting, Jonathan T. and Tolias, Andreas Savas and Torkelson, Amy and Tung, Herman and Vaishnav, Eeshit Dhaval and Van den Berge, Koen and van Velthoven, Cindy T.J. and Vanderburg, Charles R. and Veldman, Matthew B. and Vu, Minh and Wakeman, Wayne and Wang, Peng and Wang, Quanxin and Wang, Xinxin and Wang, Yimin and Wang, Yun and Welch, Joshua D. and White, Owen and Williams, Elora and Xie, Fangming and Xie, Peng and Xiong, Feng and Yang, X. William and Yanny, Anna Marie and Yao, Zizhen and Yin, Lulu and Yu, Yang and Yuan, Jing and Zeng, Hongkui and Zhang, Kun and Zhang, Meng and Zhang, Zhuzhu and Zhao, Sujun and Zhao, Xuan and Zhou, Jingtian and Zhuang, Xiaowei and Zingg, Brian (2021) A multimodal cell census and atlas of the mammalian primary motor cortex. Nature, 598 (7879). pp. 86-102. ISSN 0028-0836. doi:10.1038/s41586-021-03950-0. https://resolver.caltech.edu/CaltechAUTHORS:20201027-075126222

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	PDF (Reporting Summary) - Supplemental Material Creative Commons Attribution. 158kB
	MS Excel (Supplementary Table 1) - Supplemental Material Creative Commons Attribution. 225kB
	MS Excel (Supplementary Table 2) - Supplemental Material Creative Commons Attribution. 133kB
	PDF (Peer Review File) - Supplemental Material Creative Commons Attribution. 1MB
	Image (JPEG) (Extended Data Fig. 1: Summary of experimental and computational approaches taken and community resources generated by BICCN) - Supplemental Material Creative Commons Attribution. 546kB
	Image (JPEG) (Extended Data Fig. 2: MOp consensus cell type taxonomy) - Supplemental Material Creative Commons Attribution. 564kB
	Image (JPEG) (Extended Data Fig. 3: Epi-retro-seq links molecular cell types with distal projection targets) - Supplemental Material Creative Commons Attribution. 120kB
	Image (JPEG) (Extended Data Fig. 4: Anatomical characterization of MOp-ul neuron types) - Supplemental Material Creative Commons Attribution. 226kB
	Image (JPEG) (Extended Data Fig. 5: An integrated multimodal census and atlas of cell types in the primary motor cortex of mouse, marmoset and human) - Supplemental Material Creative Commons Attribution. 386kB
	Image (JPEG) (Extended Data Fig. 6: Identification of putative enhancer-gene pairs) - Supplemental Material Creative Commons Attribution. 557kB
	Image (JPEG) (Extended Data Fig. 7: Dot plot illustrating RNA expression levels (red) and hypo-CG-DMR motif enrichments (blue) of transcription factors (TFs) in mouse MOp subclasses) - Supplemental Material Creative Commons Attribution. 263kB
Preview	Image (JPEG) (Extended Data Table 1 Experimental and computational techniques used in this study and associated datasets) - Supplemental Material Creative Commons Attribution. 183kB
Preview	Image (JPEG) (Extended Data Table 2 Glossary) - Supplemental Material Creative Commons Attribution. 137kB

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