Feng, Huibao and Yuan, Yaomeng and Yang, Zheng and Xing, Xin-hui and Zhang, Chong (2021) Genome-wide genotype-phenotype associations in microbes. Journal of Bioscience and Bioengineering, 132 (1). pp. 1-8. ISSN 1389-1723. doi:10.1016/j.jbiosc.2021.03.011. https://resolver.caltech.edu/CaltechAUTHORS:20210423-102122913
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Abstract
The concept of a gene has been developed a lot since the Mendelian era owing to the rapid progress in molecular biology and informatics. To explore the nature of life, varieties of biological tools have been continuously established. Many achievements have been made to clarify the relationships between genotypes and phenotypes. However, it is still not completely clear that how traits of an organism are encoded by its genome. In this review, we will summarize and discuss representative works in systematical functional genomic studies in microbes. By analyzing their developmental progressions and limitations, we may have chances to design more powerful means to decipher the code of life.
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Additional Information: | © 2021 The Society for Biotechnology, Japan. Received 19 December 2020, Accepted 23 March 2021, Available online 21 April 2021. It is a great honor for C. Zhang to receive the Young Asian Biotechnologist Prize 2020 awarded by the Society for Biotechnology, Japan. This paper is supported by the National Key R&D Program of China [2018YFA0901500]; the Program of National Natural Science Foundation of China [U2032210, 21938004, 21676156]. | ||||||||||||
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Subject Keywords: | Genotype-phenotype associations; Arrayed; Pooled; Genome-wide; Microbes | ||||||||||||
Issue or Number: | 1 | ||||||||||||
DOI: | 10.1016/j.jbiosc.2021.03.011 | ||||||||||||
Record Number: | CaltechAUTHORS:20210423-102122913 | ||||||||||||
Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20210423-102122913 | ||||||||||||
Official Citation: | Huibao Feng, Yaomeng Yuan, Zheng Yang, Xin-hui Xing, Chong Zhang, Genome-wide genotype-phenotype associations in microbes, Journal of Bioscience and Bioengineering, Volume 132, Issue 1, 2021, Pages 1-8, ISSN 1389-1723, https://doi.org/10.1016/j.jbiosc.2021.03.011. (https://www.sciencedirect.com/science/article/pii/S1389172321000657) | ||||||||||||
Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||||||||
ID Code: | 108811 | ||||||||||||
Collection: | CaltechAUTHORS | ||||||||||||
Deposited By: | Tony Diaz | ||||||||||||
Deposited On: | 23 Apr 2021 23:28 | ||||||||||||
Last Modified: | 23 Jun 2021 19:42 |
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