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Multimodal integration across spatiotemporal scales to guide invertebrate locomotion

Mongeau, Jean-Michel and Schweikert, Lorian E. and Davis, Alexander L. and Reichert, Michael S. and Kanwal, Jessleen K. (2021) Multimodal integration across spatiotemporal scales to guide invertebrate locomotion. Integrative and Comparative Biology . ISSN 1540-7063. doi:10.1093/icb/icab041. (In Press) https://resolver.caltech.edu/CaltechAUTHORS:20210525-160331176

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Abstract

Locomotion is a hallmark of organisms that has enabled adaptive radiation to an extraordinarily diverse class of ecological niches, and allows animals to move across vast distances. Sampling from multiple sensory modalities enables animals to acquire rich information to guide locomotion. Locomotion without sensory feedback is haphazard, therefore sensory and motor systems have evolved complex interactions to generate adaptive behavior. Notably, sensory-guided locomotion acts over broad spatial and temporal scales to permit goal-seeking behavior, whether to localize food by tracking an attractive odor plume or to search for a potential mate. How does the brain integrate multimodal stimuli over different temporal and spatial scales to effectively control behavior? In this review, we classify locomotion into three ordinally ranked hierarchical layers that act over distinct spatiotemporal scales: stabilization, motor primitives, and higher-order tasks, respectively. We discuss how these layers present unique challenges and opportunities for sensorimotor integration. We focus on recent advances in invertebrate locomotion due to their accessible neural and mechanical signals from the whole brain, limbs and sensors. Throughout, we emphasize neural-level description of computations for multimodal integration in genetic model systems, including the fruit fly, Drosophila melanogaster, and the yellow fever mosquito, Aedes aegypti. We identify that summation (e.g. gating) and weighting—which are inherent computations of spiking neurons—underlie multimodal integration across spatial and temporal scales, therefore suggesting collective strategies to guide locomotion.


Item Type:Article
Related URLs:
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https://doi.org/10.1093/icb/icab041DOIArticle
Additional Information:© The Author(s) 2021. Published by Oxford University Press on behalf of the Society for Integrative and Comparative Biology. This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model). Published: 01 May 2021.
DOI:10.1093/icb/icab041
Record Number:CaltechAUTHORS:20210525-160331176
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20210525-160331176
Official Citation:Jean-Michel Mongeau, Lorian E Schweikert, Alexander L Davis, Michael S Reichert, Jessleen K Kanwal, Multimodal integration across spatiotemporal scales to guide invertebrate locomotion, Integrative and Comparative Biology, 2021, icab041, https://doi.org/10.1093/icb/icab041
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:109251
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:26 May 2021 18:02
Last Modified:26 May 2021 18:02

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