Amberland	Yosef Lab	Liu Lab	Guan Lab	RNILabs	
						
Parameter estimates	Feature extraction	Edit frequencies 	Edit frequencies	Edit frequencies	Feature extraction	
Estimation method	Gradient boosting machines	Maximum likelihood	Tree search	Random Forest	Gradient Boosting	
Tree construction	Clustering of sister probabilities	Weighted Maximum parsimony	Hierarchical clustering	Custom hierarchical clustering	Custom hierarchical 
clustering	
Parallel CPU	Feature extraction	No	No	Yes	Yes	
Solution	Unique	Unique	Unique	Unique	Unique	
Implementation	R 	Python	Python	Python	Python	
Availability 	https://github.com/rretkute/ml_cell_lineage_reconstruction 	https://github.com/YosefLab/Cassiopeia	https://github.com/JasperYH/lineage_tracing	https://github.com/GuanLab/Cell-Linage-Reconstruction	https://www.synapse.org/#!Synapse:syn21559988/wiki/604198