A Caltech Library Service

Safety-Critical Control of Compartmental Epidemiological Models with Measurement Delays

Molnár, Tamás G. and Singletary, Andrew W. and Orosz, Gábor and Ames, Aaron D. (2021) Safety-Critical Control of Compartmental Epidemiological Models with Measurement Delays. In: 2021 American Control Conference (ACC). IEEE , Piscataway, NJ, pp. 1052-1057. ISBN 978-1-6654-4197-1.

Full text is not posted in this repository. Consult Related URLs below.

Use this Persistent URL to link to this item:


We introduce a methodology to guarantee safety against the spread of infectious diseases by viewing epidemiological models as control systems and by considering human interventions (such as quarantining or social distancing) as control input. We consider a generalized compartmental model that represents the form of the most popular epidemiological models and we design safety-critical controllers that formally guarantee safe evolution with respect to keeping certain populations of interest under prescribed safe limits. Furthermore, we discuss how measurement delays originated from incubation period and testing delays affect safety and how delays can be compensated via predictor feedback. We demonstrate our results by synthesizing active intervention policies that bound the number of infections, hospitalizations and deaths for epidemiological models capturing the spread of COVID-19 in the USA.

Item Type:Book Section
Related URLs:
URLURL TypeDescription ItemJournal Article
Molnár, Tamás G.0000-0002-9379-7121
Singletary, Andrew W.0000-0001-6635-4256
Orosz, Gábor0000-0002-9000-3736
Ames, Aaron D.0000-0003-0848-3177
Additional Information:© 2021 AACC. The authors would like to thank Franca Hoffmann and Gábor Stépán for the valuable discussions on this topic. This research is supported in part by the National Science Foundation, CPS Award #1932091.
Funding AgencyGrant Number
Record Number:CaltechAUTHORS:20210825-155129665
Persistent URL:
Official Citation:T. G. Molnár, A. W. Singletary, G. Orosz and A. D. Ames, "Safety-Critical Control of Compartmental Epidemiological Models with Measurement Delays," 2021 American Control Conference (ACC), 2021, pp. 1052-1057, doi: 10.23919/ACC50511.2021.9482737
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:110420
Deposited By: Tony Diaz
Deposited On:25 Aug 2021 16:52
Last Modified:25 Aug 2021 16:52

Repository Staff Only: item control page