Sacher, Wesley D. and Chen, Fu-Der and Moradi-Chameh, Homeira and Liu, Xinyu and Felts Almog, Ilan and Lordello, Thomas and Chang, Michael and Naderian, Azadeh and Fowler, Trevor M. and Segev, Eran and Xue, Tianyuan and Mahallati, Sara and Valiante, Taufik A. and Moreaux, Laurent C. and Poon, Joyce K. S. and Roukes, Michael L. (2022) Optical phased array neural probes for beam-steering in brain tissue. Optics Letters, 47 (5). pp. 1073-1076. ISSN 0146-9592. doi:10.1364/OL.441609. https://resolver.caltech.edu/CaltechAUTHORS:20210831-204006744
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Abstract
Implantable silicon neural probes with integrated nanophotonic waveguides can deliver patterned dynamic illumination into brain tissue at depth. Here, we introduce neural probes with integrated optical phased arrays and demonstrate optical beam steering in vitro. Beam formation in brain tissue is simulated and characterized. The probes are used for optogenetic stimulation and calcium imaging.
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| Additional Information: | © 2022 Optica Publishing Group. Received 26 August 2021; revised 28 November 2021; accepted 9 December 2021; posted 13 December 2021; published 18 February 2022. Funding: National Institutes of Health (NS090596, NS099726); Caltech Kavli Nanoscience Institute; Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada. The authors declare no conflicts of interest. Data availability: Data underlying the results presented in this Letter are not publicly available at this time but may be obtained from the authors upon reasonable request. | ||||||||||||
| Group: | Kavli Nanoscience Institute | ||||||||||||
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| Issue or Number: | 5 | ||||||||||||
| DOI: | 10.1364/OL.441609 | ||||||||||||
| Record Number: | CaltechAUTHORS:20210831-204006744 | ||||||||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20210831-204006744 | ||||||||||||
| Official Citation: | Wesley D. Sacher, Fu-Der Chen, Homeira Moradi-Chameh, Xinyu Liu, Ilan Felts Almog, Thomas Lordello, Michael Chang, Azadeh Naderian, Trevor M. Fowler, Eran Segev, Tianyuan Xue, Sara Mahallati, Taufik A. Valiante, Laurent C. Moreaux, Joyce K. S. Poon, and Michael L. Roukes, "Optical phased array neural probes for beam-steering in brain tissue," Opt. Lett. 47, 1073-1076 (2022); DOI: 10.1364/OL.441609 | ||||||||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||||||||
| ID Code: | 110665 | ||||||||||||
| Collection: | CaltechAUTHORS | ||||||||||||
| Deposited By: | George Porter | ||||||||||||
| Deposited On: | 01 Sep 2021 14:36 | ||||||||||||
| Last Modified: | 05 Apr 2022 20:03 |
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