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Optical phased array neural probes for beam-steering in brain tissue

Sacher, Wesley D. and Chen, Fu-Der and Moradi-Chameh, Homeira and Liu, Xinyu and Felts Almog, Ilan and Lordello, Thomas and Chang, Michael and Naderian, Azadeh and Fowler, Trevor M. and Segev, Eran and Xue, Tianyuan and Mahallati, Sara and Valiante, Taufik A. and Moreaux, Laurent C. and Poon, Joyce K. S. and Roukes, Michael L. (2021) Optical phased array neural probes for beam-steering in brain tissue. . (Unpublished)

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Implantable silicon neural probes with integrated nanophotonic waveguides can deliver patterned dynamic illumination into brain tissue at depth. Here, we introduce neural probes with integrated optical phased arrays and demonstrate optical beam steering in vitro. Beam formation in brain tissue was simulated and characterized. The probes were used for optogenetic stimulation and calcium imaging.

Item Type:Report or Paper (Discussion Paper)
Related URLs:
URLURL TypeDescription Paper
Sacher, Wesley D.0000-0003-3306-4556
Valiante, Taufik A.0000-0002-3443-3790
Moreaux, Laurent C.0000-0003-1276-5062
Poon, Joyce K. S.0000-0002-3691-4344
Roukes, Michael L.0000-0002-2916-6026
Additional Information:Attribution 4.0 International (CC BY 4.0) Funding. National Institutes of Health (NS090596, NS099726); Caltech Kavli Nanoscience Institute; Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canadian Foundation for Innovation. The authors declare no conflicts of interest.
Group:Kavli Nanoscience Institute
Funding AgencyGrant Number
Kavli Nanoscience InstituteUNSPECIFIED
Canadian Institutes of Health Research (CIHR)UNSPECIFIED
Natural Sciences and Engineering Research Council of Canada (NSERC)UNSPECIFIED
Canada Foundation for InnovationUNSPECIFIED
Record Number:CaltechAUTHORS:20210831-204006744
Persistent URL:
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:110665
Deposited By: George Porter
Deposited On:01 Sep 2021 14:36
Last Modified:01 Sep 2021 14:36

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