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Ir(III) and Ru(II) Complexes in Photoredox Catalysis and Photodynamic Therapy: A New Paradigm towards Anticancer Applications

Raza, Md Kausar and Noor, Aisha and Samantaray, Paresh Kumar (2021) Ir(III) and Ru(II) Complexes in Photoredox Catalysis and Photodynamic Therapy: A New Paradigm towards Anticancer Applications. ChemBioChem . ISSN 1439-4227. doi:10.1002/cbic.202100469. (In Press) https://resolver.caltech.edu/CaltechAUTHORS:20211008-224614978

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Abstract

Individually, photoredox catalysis (PC) and photodynamic therapy (PDT) are well-established concepts that have experienced a remarkable resurgence in recent years, leading to significant progress in organic synthesis for PC and clinical approval of anticancer drugs for PDT. But, very recently, new photoredox catalyst systems based on Ir(III) and Ru(II) complexes have garnered significant interest because they can simultaneously be used as PDT agents apart from their demonstrated PC activity. This highlight discusses the unique PC behavior of emerging Ir(III)- and Ru(II)-based systems while also examining their potential PDT activity in cancer treatment.


Item Type:Article
Related URLs:
URLURL TypeDescription
https://doi.org/10.1002/cbic.202100469DOIArticle
ORCID:
AuthorORCID
Raza, Md Kausar0000-0002-9175-198X
Noor, Aisha0000-0002-6049-7448
Samantaray, Paresh Kumar0000-0003-2533-929X
Additional Information:© 2021 Wiley-VCH. Version of Record online: 06 October 2021. Accepted manuscript online: 24 September 2021. Manuscript revised: 23 September 2021. Manuscript received: 03 September 2021. P.K.S. acknowledges USIEF for supporting the Fulbright-Nehru Postdoctoral Fellowship. The authors declare no conflict of interest.
Funders:
Funding AgencyGrant Number
United States-India Educational FoundationUNSPECIFIED
Subject Keywords:anticancer treatment; Ir(III) and Ru(II) complexes; photodynamic therapy; photoredox catalysis
DOI:10.1002/cbic.202100469
Record Number:CaltechAUTHORS:20211008-224614978
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20211008-224614978
Official Citation:Raza, M.K., Noor, A. and Samantaray, P.K. (2021), Ir(III) and Ru(II) Complexes in Photoredox Catalysis and Photodynamic Therapy: A New Paradigm towards Anticancer Applications. ChemBioChem. https://doi.org/10.1002/cbic.202100469
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:111316
Collection:CaltechAUTHORS
Deposited By: George Porter
Deposited On:12 Oct 2021 20:21
Last Modified:12 Oct 2021 20:22

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