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The amphioxus genome and the evolution of the chordate karyotype

Putnam, Nicholas H. and Butts, Thomas and Ferrier, David E. K. and Furlong, Rebecca F. and Hellsten, Uffe and Kawashima, Takeshi and Robinson-Rechavi, Marc and Shoguchi, Eiichi and Terry, Astrid and Yu, Jr-Kai and Benito-Gutiérrez, Èlia and Dubchak, Inna and Garcia-Fernàdez, Jordi and Gibson-Brown, Jeremy J. and Grigoriev, Igor V. and Horton, Amy C. and de Jong, Pieter J. and Jurka, Jerzy and Kapitonov, Vladimir V. and Kohara, Yuji and Kuroki, Yoko and Lindquist, Erika and Lucas, Susan and Osoegawa, Kazutoyo and Pennacchio, Len A. and Salamov, Asaf A. and Satou, Yutaka and Sauka-Spengler, Tatjana and Schumtz, Jeremy and Shin-I, Tadasu and Toyoda, Atsushi and Fujiyama, Asao and Holland, Linda Z. and Holland, Peter W. H. and Satoh, Nori and Rokhsar, Daniel S. and Bronner-Fraser, Marianne (2008) The amphioxus genome and the evolution of the chordate karyotype. Nature, 453 (7198). pp. 1064-1072. ISSN 0028-0836. http://resolver.caltech.edu/CaltechAUTHORS:PUTnat08

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Abstract

Lancelets ('amphioxus') are the modern survivors of an ancient chordate lineage, with a fossil record dating back to the Cambrian period. Here we describe the structure and gene content of the highly polymorphic approx520-megabase genome of the Florida lancelet Branchiostoma floridae, and analyse it in the context of chordate evolution. Whole-genome comparisons illuminate the murky relationships among the three chordate groups (tunicates, lancelets and vertebrates), and allow not only reconstruction of the gene complement of the last common chordate ancestor but also partial reconstruction of its genomic organization, as well as a description of two genome-wide duplications and subsequent reorganizations in the vertebrate lineage. These genome-scale events shaped the vertebrate genome and provided additional genetic variation for exploitation during vertebrate evolution.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1038/nature06967DOIArticle
http://www.nature.com/nature/journal/v453/n7198/abs/nature06967.htmlPublisherArticle
http://www.nature.com/nature/journal/v453/n7198/suppinfo/nature06967.htmlPublisherSupplementary Information
http://rdcu.be/fGInPublisherFree ReadCube access
ORCID:
AuthorORCID
Bronner-Fraser, Marianne0000-0003-4274-1862
Additional Information:This article is distributed under the terms of the Creative Commons Attribution-Non-Commercial-Share Alike licence (http://creativecommons.org/licenses/by-nc-sa/3.0/), which permits distribution, and reproduction in any medium, provided the original author and source are credited. This licence does not permit commercial exploitation, and derivative works must be licensed under the same or similar licence. Received 8 March 2008; Accepted 4 April 2008. This work was performed under the auspices of the US Department of Energy's Office of Science, Biological and Environmental Research Program, and by the University of California, Lawrence Livermore National Laboratory under contract number W-7405-Eng-48, Lawrence Berkeley National Laboratory under contract number DE-AC02-05CH11231, and Los Alamos National Laboratory under contract number DE-AC02-06NA25396. The Center for Integrative Genomics is supported by a grant from the Gordon and Betty Moore Foundation. D.S.R. acknowledges support from R. A. Melmon. This work was funded by grants from Ministerio de Educacin y Ciencia (J.G.-F.), MEXT, Japan (N.S., A.F., and Y.K.), the 21st Century and Global COEs at Kyoto University (N.S.), grant number P41LM from the National Library of Medicine (J.J. and V.V.K.), BBSRC (T.B. and D.E.K.F.) and the Wellcome Trust (P.W.H.H.).
Funders:
Funding AgencyGrant Number
Department of Energy (DOE)W-7405-ENG-48
Department of Energy (DOE)DE-AC02-05CH11231
Department of Energy (DOE)DE-AC02-06NA25396
Gordon and Betty Moore FoundationUNSPECIFIED
R. A. MelmonUNSPECIFIED
Ministerio de Educacin y CienciaUNSPECIFIED
Ministry of Education, Culture, Sports, Science and Technology (MEXT)UNSPECIFIED
21st Century and Global COEsUNSPECIFIED
National Library of MedicineP41LM
Biotechnology and Biological Sciences Research Council (BBSRC)UNSPECIFIED
Wellcome TrustUNSPECIFIED
Issue or Number:7198
Record Number:CaltechAUTHORS:PUTnat08
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:PUTnat08
Usage Policy:This article is distributed under the terms of the Creative Commons Attribution-Non-Commercial-Share Alike licence (http://creativecommons.org/licenses/by-nc-sa/3.0/), which permits distribution, and reproduction in any medium, provided the original author and source are credited. This licence does not permit commercial exploitation, and derivative works must be licensed under the same or similar licence.
ID Code:11220
Collection:CaltechAUTHORS
Deposited By: Archive Administrator
Deposited On:25 Jul 2008 00:29
Last Modified:29 Sep 2017 18:00

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