Holman, Elizabeth A. and Li, Dong and Ashby, Paul D. and Zuckermann, Ronald N. and Sternberg, Paul (2021) Designing optically transparent photo-crosslinked peptoid nanosheets for imaging applications. In: 262nd ACS National Meeting & Exposition, 22-26 August 2021, Atlanta, GA. https://resolver.caltech.edu/CaltechAUTHORS:20211217-000135083
Full text is not posted in this repository. Consult Related URLs below.
Use this Persistent URL to link to this item: https://resolver.caltech.edu/CaltechAUTHORS:20211217-000135083
Abstract
Peptoid bilayer nanosheets are a new class of biocompatible 2D nanomaterial with broad applications, including sensing, membrane mimicry and pathogen binding. They are formed from the self-assembly of sequence-defined peptoid chains and can be readily functionalized to tune their properties. In order to broaden their utility, there is a need to improve their mech. stability. Here, we create nanosheets that can function as a mech. robust, optically transparent interfacial barrier for covering microfluidic channels, microscopy grids and other sample chambers. This barrier would increase hydration control in otherwise open-channel environments, permitting water-sensitive, non-destructive IR spectroscopy to be incorporated into multimodal imaging platforms. Therefore, we explored new peptoid analogs contg. photo-crosslinkable side chains that can form intra-monolayer as well as inter-layer covalent bonds. These constructs can be co-assembled in various ratios to achieve a range of desirable mech. properties to provide a new route to ultrathin, mech. robust, 2D nanomaterials that serve as optically transparent interfacial barriers for a variety of imaging techniques.
Item Type: | Conference or Workshop Item (Paper) | ||||||
---|---|---|---|---|---|---|---|
Related URLs: |
| ||||||
ORCID: |
| ||||||
Additional Information: | © 2021 American Chemical Society. | ||||||
Record Number: | CaltechAUTHORS:20211217-000135083 | ||||||
Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20211217-000135083 | ||||||
Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||
ID Code: | 112496 | ||||||
Collection: | CaltechAUTHORS | ||||||
Deposited By: | Tony Diaz | ||||||
Deposited On: | 17 Dec 2021 17:34 | ||||||
Last Modified: | 17 Dec 2021 17:34 |
Repository Staff Only: item control page